Schaible AM - Search Results

1

Progesterone rapidly down-regulates the biosynthesis of 5-lipoxygenase products in human primary monocytes.

Pergola C, Schaible AM, Nikels F, Dodt G, Northoff H, Werz O. Pergola C, et al. Among authors: schaible am. Pharmacol Res. 2015 Apr;94:42-50. doi: 10.1016/j.phrs.2015.01.007. Epub 2015 Feb 11. Pharmacol Res. 2015. PMID: 25681061

2

High capacity for leukotriene biosynthesis in peripheral blood during pregnancy.

Schaible AM, Koeberle A, Northoff H, Lawrenz B, Weinigel C, Barz D, Werz O, Pergola C. Schaible AM, et al. Prostaglandins Leukot Essent Fatty Acids. 2013 Sep;89(4):245-55. doi: 10.1016/j.plefa.2013.06.004. Epub 2013 Jul 16. Prostaglandins Leukot Essent Fatty Acids. 2013. PMID: 23870194

3

Caulerpenyne and related bis-enol esters are novel-type inhibitors of human 5-lipoxygenase.

Richter P, Schubert G, Schaible AM, Cavas L, Werz O, Pohnert G. Richter P, et al. Among authors: schaible am. ChemMedChem. 2014 Aug;9(8):1655-9. doi: 10.1002/cmdc.201402065. Epub 2014 Apr 11. ChemMedChem. 2014. PMID: 24729578

4

Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.

Schaible AM, Filosa R, Temml V, Krauth V, Matteis M, Peduto A, Bruno F, Luderer S, Roviezzo F, Di Mola A, de Rosa M, D'Agostino B, Weinigel C, Barz D, Koeberle A, Pergola C, Schuster D, Werz O. Schaible AM, et al. Br J Pharmacol. 2014 May;171(9):2399-412. doi: 10.1111/bph.12592. Br J Pharmacol. 2014. PMID: 24467325 Free PMC article.

5

A novel C(28)-hydroxylated lupeolic acid suppresses the biosynthesis of eicosanoids through inhibition of cytosolic phospholipase A(2).

Verhoff M, Seitz S, Northoff H, Jauch J, Schaible AM, Werz O. Verhoff M, et al. Among authors: schaible am. Biochem Pharmacol. 2012 Sep 1;84(5):681-91. doi: 10.1016/j.bcp.2012.06.016. Epub 2012 Jun 23. Biochem Pharmacol. 2012. PMID: 22732453

6

Chemometrics-guided development of a cyclodextrin-modified micellar electrokinetic chromatography method with head-column field amplified sample stacking for the analysis of 5-lipoxygenase metabolites.

Abromeit H, Schaible AM, Werz O, Scriba GK. Abromeit H, et al. Among authors: schaible am. J Chromatogr A. 2012 Dec 7;1267:217-23. doi: 10.1016/j.chroma.2012.08.001. Epub 2012 Aug 4. J Chromatogr A. 2012. PMID: 22909891

7

Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin.

Schaible AM, Traber H, Temml V, Noha SM, Filosa R, Peduto A, Weinigel C, Barz D, Schuster D, Werz O. Schaible AM, et al. Biochem Pharmacol. 2013 Aug 15;86(4):476-86. doi: 10.1016/j.bcp.2013.04.015. Epub 2013 Apr 24. Biochem Pharmacol. 2013. PMID: 23623753

8

Indirubin core structure of glycogen synthase kinase-3 inhibitors as novel chemotype for intervention with 5-lipoxygenase.

Pergola C, Gaboriaud-Kolar N, Jestädt N, König S, Kritsanida M, Schaible AM, Li H, Garscha U, Weinigel C, Barz D, Albring KF, Huber O, Skaltsounis AL, Werz O. Pergola C, et al. Among authors: schaible am. J Med Chem. 2014 May 8;57(9):3715-23. doi: 10.1021/jm401740w. Epub 2014 Apr 17. J Med Chem. 2014. PMID: 24697244

9

Novel series of benzoquinones with high potency against 5-lipoxygenase in human polymorphonuclear leukocytes.

Filosa R, Peduto A, Schaible AM, Krauth V, Weinigel C, Barz D, Petronzi C, Bruno F, Roviezzo F, Spaziano G, D'Agostino B, De Rosa M, Werz O. Filosa R, et al. Among authors: schaible am. Eur J Med Chem. 2015 Apr 13;94:132-9. doi: 10.1016/j.ejmech.2015.02.042. Epub 2015 Feb 24. Eur J Med Chem. 2015. PMID: 25765759

10

The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.

Schaible AM, Filosa R, Krauth V, Temml V, Pace S, Garscha U, Liening S, Weinigel C, Rummler S, Schieferdecker S, Nett M, Peduto A, Collarile S, Scuotto M, Roviezzo F, Spaziano G, de Rosa M, Stuppner H, Schuster D, D'Agostino B, Werz O. Schaible AM, et al. Biochem Pharmacol. 2016 Jul 15;112:60-71. doi: 10.1016/j.bcp.2016.04.019. Epub 2016 May 5. Biochem Pharmacol. 2016. PMID: 27157409

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