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Insights into alternative splicing of sarcomeric genes in the heart.
Weeland CJ, van den Hoogenhof MM, Beqqali A, Creemers EE. Weeland CJ, et al. Among authors: van den hoogenhof mm. J Mol Cell Cardiol. 2015 Apr;81:107-13. doi: 10.1016/j.yjmcc.2015.02.008. Epub 2015 Feb 12. J Mol Cell Cardiol. 2015. PMID: 25683494 Review.
The microRNA-15 family inhibits the TGFβ-pathway in the heart.
Tijsen AJ, van der Made I, van den Hoogenhof MM, Wijnen WJ, van Deel ED, de Groot NE, Alekseev S, Fluiter K, Schroen B, Goumans MJ, van der Velden J, Duncker DJ, Pinto YM, Creemers EE. Tijsen AJ, et al. Among authors: van den hoogenhof mm, van der made i, van der velden j, van deel ed. Cardiovasc Res. 2014 Oct 1;104(1):61-71. doi: 10.1093/cvr/cvu184. Epub 2014 Aug 7. Cardiovasc Res. 2014. PMID: 25103110
Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling.
Medzikovic L, Schumacher CA, Verkerk AO, van Deel ED, Wolswinkel R, van der Made I, Bleeker N, Cakici D, van den Hoogenhof MM, Meggouh F, Creemers EE, Remme CA, Baartscheer A, de Winter RJ, de Vries CJ, Arkenbout EK, de Waard V. Medzikovic L, et al. Among authors: van den hoogenhof mm, van der made i, van deel ed. Sci Rep. 2015 Oct 21;5:15404. doi: 10.1038/srep15404. Sci Rep. 2015. PMID: 26486271 Free PMC article.
A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism.
Beqqali A, Bollen IA, Rasmussen TB, van den Hoogenhof MM, van Deutekom HW, Schafer S, Haas J, Meder B, Sørensen KE, van Oort RJ, Mogensen J, Hubner N, Creemers EE, van der Velden J, Pinto YM. Beqqali A, et al. Among authors: van den hoogenhof mm, van deutekom hw, van der velden j, van oort rj. Cardiovasc Res. 2016 Oct;112(1):452-63. doi: 10.1093/cvr/cvw192. Epub 2016 Aug 5. Cardiovasc Res. 2016. PMID: 27496873
RBM20 Regulates Circular RNA Production From the Titin Gene.
Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM. Khan MA, et al. Among authors: van den hoogenhof mm, van der made i, van der velden j. Circ Res. 2016 Oct 14;119(9):996-1003. doi: 10.1161/CIRCRESAHA.116.309568. Epub 2016 Aug 16. Circ Res. 2016. PMID: 27531932
The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy.
Damanafshan A, Elzenaar I, Samson-Couterie B, van der Made I, Bourajjaj M, van den Hoogenhof MM, van Veen HA, Picavet DI, Beqqali A, Ehler E, De Windt LJ, Pinto YM, van Oort RJ. Damanafshan A, et al. Among authors: van den hoogenhof mm, van veen ha, van der made i, van oort rj. Cardiovasc Res. 2018 Sep 1;114(11):1474-1486. doi: 10.1093/cvr/cvy091. Cardiovasc Res. 2018. PMID: 29648621
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