Theodorescu D - Search Results

1

Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation.

Zhao D, Besser AH, Wander SA, Sun J, Zhou W, Wang B, Ince T, Durante MA, Guo W, Mills G, Theodorescu D, Slingerland J. Zhao D, et al. Among authors: theodorescu d. Oncogene. 2015 Oct;34(43):5447-59. doi: 10.1038/onc.2014.473. Epub 2015 Feb 16. Oncogene. 2015. PMID: 25684140 Free PMC article.

2

Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia.

Wu Y, McRoberts K, Berr SS, Frierson HF Jr, Conaway M, Theodorescu D. Wu Y, et al. Among authors: theodorescu d. Oncogene. 2007 Feb 1;26(5):765-73. doi: 10.1038/sj.onc.1209835. Epub 2006 Jul 31. Oncogene. 2007. PMID: 16878152

3

Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

Nickerson ML, Witte N, Im KM, Turan S, Owens C, Misner K, Tsang SX, Cai Z, Wu S, Dean M, Costello JC, Theodorescu D. Nickerson ML, et al. Among authors: theodorescu d. Oncogene. 2017 Jan 5;36(1):35-46. doi: 10.1038/onc.2016.172. Epub 2016 Jun 6. Oncogene. 2017. PMID: 27270441 Free PMC article.

4

A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer.

Fantini D, Glaser AP, Rimar KJ, Wang Y, Schipma M, Varghese N, Rademaker A, Behdad A, Yellapa A, Yu Y, Sze CC, Wang L, Zhao Z, Crawford SE, Hu D, Licht JD, Collings CK, Bartom E, Theodorescu D, Shilatifard A, Meeks JJ. Fantini D, et al. Among authors: theodorescu d. Oncogene. 2018 Apr;37(14):1911-1925. doi: 10.1038/s41388-017-0099-6. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367767 Free PMC article.

5

Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways.

Sheta EA, Trout H, Gildea JJ, Harding MA, Theodorescu D. Sheta EA, et al. Among authors: theodorescu d. Oncogene. 2001 Nov 15;20(52):7624-34. doi: 10.1038/sj.onc.1204972. Oncogene. 2001. PMID: 11753640

6

Expression profiling of Ral-depleted bladder cancer cells identifies RREB-1 as a novel transcriptional Ral effector.

Oxford G, Smith SC, Hampton G, Theodorescu D. Oxford G, et al. Among authors: theodorescu d. Oncogene. 2007 Nov 1;26(50):7143-52. doi: 10.1038/sj.onc.1210521. Epub 2007 May 14. Oncogene. 2007. PMID: 17496927

7

Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration.

Wu Y, Siadaty MS, Berens ME, Hampton GM, Theodorescu D. Wu Y, et al. Among authors: theodorescu d. Oncogene. 2008 Nov 6;27(52):6679-89. doi: 10.1038/onc.2008.264. Epub 2008 Aug 25. Oncogene. 2008. PMID: 18724390 Free PMC article.

8

PKCα phosphorylation of RhoGDI2 at Ser31 disrupts interactions with Rac1 and decreases GDI activity.

Griner EM, Churchill ME, Brautigan DL, Theodorescu D. Griner EM, et al. Among authors: theodorescu d. Oncogene. 2013 Feb 21;32(8):1010-7. doi: 10.1038/onc.2012.124. Epub 2012 Apr 2. Oncogene. 2013. PMID: 22469974 Free PMC article.

9

An Osteopontin/CD44 Axis in RhoGDI2-Mediated Metastasis Suppression.

Ahmed M, Sottnik JL, Dancik GM, Sahu D, Hansel DE, Theodorescu D, Schwartz MA. Ahmed M, et al. Among authors: theodorescu d. Cancer Cell. 2016 Sep 12;30(3):432-443. doi: 10.1016/j.ccell.2016.08.002. Epub 2016 Sep 1. Cancer Cell. 2016. PMID: 27593345 Free PMC article.

10

Metastatic cells are preferentially vulnerable to lysosomal inhibition.

Morgan MJ, Fitzwalter BE, Owens CR, Powers RK, Sottnik JL, Gamez G, Costello JC, Theodorescu D, Thorburn A. Morgan MJ, et al. Among authors: theodorescu d. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8479-E8488. doi: 10.1073/pnas.1706526115. Epub 2018 Aug 20. Proc Natl Acad Sci U S A. 2018. PMID: 30127018 Free PMC article.

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