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Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself.
McCrudden CM, O'Rourke MG, Cherry KE, Yuen HF, O'Rourke D, Babur M, Telfer BA, Thomas HD, Keane P, Nambirajan T, Hagan C, O'Sullivan JM, Shaw C, Williams KJ, Curtin NJ, Hirst DG, Robson T. McCrudden CM, et al. Among authors: hirst dg. PLoS One. 2015 Feb 17;10(2):e0118187. doi: 10.1371/journal.pone.0118187. eCollection 2015. PLoS One. 2015. PMID: 25689628 Free PMC article.
Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase: a contributory factor to chemopotentiation in vivo?
Ali M, Telfer BA, McCrudden C, O'Rourke M, Thomas HD, Kamjoo M, Kyle S, Robson T, Shaw C, Hirst DG, Curtin NJ, Williams KJ. Ali M, et al. Among authors: hirst dg. Clin Cancer Res. 2009 Oct 1;15(19):6106-12. doi: 10.1158/1078-0432.CCR-09-0398. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789326 Free PMC article.
Targeting nitric oxide for cancer therapy.
Hirst D, Robson T. Hirst D, et al. J Pharm Pharmacol. 2007 Jan;59(1):3-13. doi: 10.1211/jpp.59.1.0002. J Pharm Pharmacol. 2007. PMID: 17227615 Review.
Nitric oxide physiology and pathology.
Hirst DG, Robson T. Hirst DG, et al. Methods Mol Biol. 2011;704:1-13. doi: 10.1007/978-1-61737-964-2_1. Methods Mol Biol. 2011. PMID: 21161625 Review.
Nitrosative stress in cancer therapy.
Hirst DG, Robson T. Hirst DG, et al. Front Biosci. 2007 May 1;12:3406-18. doi: 10.2741/2322. Front Biosci. 2007. PMID: 17485309 Review.
Gold nanoparticles as novel agents for cancer therapy.
Jain S, Hirst DG, O'Sullivan JM. Jain S, et al. Among authors: hirst dg. Br J Radiol. 2012 Feb;85(1010):101-13. doi: 10.1259/bjr/59448833. Epub 2011 Oct 18. Br J Radiol. 2012. PMID: 22010024 Free PMC article. Review.
158 results