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Molecular architecture of 4E-BP translational inhibitors bound to eIF4E.
Peter D, Igreja C, Weber R, Wohlbold L, Weiler C, Ebertsch L, Weichenrieder O, Izaurralde E. Peter D, et al. Among authors: weber r. Mol Cell. 2015 Mar 19;57(6):1074-1087. doi: 10.1016/j.molcel.2015.01.017. Epub 2015 Feb 19. Mol Cell. 2015. PMID: 25702871 Free article.
HELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs.
Hanet A, Räsch F, Weber R, Ruscica V, Fauser M, Raisch T, Kuzuoğlu-Öztürk D, Chang CT, Bhandari D, Igreja C, Wohlbold L. Hanet A, et al. Among authors: weber r. Life Sci Alliance. 2019 Sep 30;2(5):e201900405. doi: 10.26508/lsa.201900405. Print 2019 Oct. Life Sci Alliance. 2019. PMID: 31570513 Free PMC article.
4E-T-bound mRNAs are stored in a silenced and deadenylated form.
Räsch F, Weber R, Izaurralde E, Igreja C. Räsch F, et al. Among authors: weber r. Genes Dev. 2020 Jun 1;34(11-12):847-860. doi: 10.1101/gad.336073.119. Epub 2020 Apr 30. Genes Dev. 2020. PMID: 32354837 Free PMC article.
3,925 results