Giaccia AJ - Search Results

1

Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.

Jiang D, LaGory EL, Kenzelmann Brož D, Bieging KT, Brady CA, Link N, Abrams JM, Giaccia AJ, Attardi LD. Jiang D, et al. Among authors: giaccia aj. Cell Rep. 2015 Feb 24;10(7):1096-109. doi: 10.1016/j.celrep.2015.01.043. Epub 2015 Feb 19. Cell Rep. 2015. PMID: 25704813 Free PMC article.

2

A low-carb diet kills tumor cells with a mutant p53 tumor suppressor gene: the Atkins diet suppresses tumor growth.

LaGory EL, Giaccia AJ. LaGory EL, et al. Among authors: giaccia aj. Cell Cycle. 2013 Mar 1;12(5):718-9. doi: 10.4161/cc.23948. Epub 2013 Feb 19. Cell Cycle. 2013. PMID: 23422857 Free PMC article. No abstract available.

3

Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma.

LaGory EL, Wu C, Taniguchi CM, Ding CC, Chi JT, von Eyben R, Scott DA, Richardson AD, Giaccia AJ. LaGory EL, et al. Among authors: giaccia aj. Cell Rep. 2015 Jul 7;12(1):116-127. doi: 10.1016/j.celrep.2015.06.006. Epub 2015 Jun 25. Cell Rep. 2015. PMID: 26119730 Free PMC article.

4

Genome-wide analysis of p53 under hypoxic conditions.

Hammond EM, Mandell DJ, Salim A, Krieg AJ, Johnson TM, Shirazi HA, Attardi LD, Giaccia AJ. Hammond EM, et al. Among authors: giaccia aj. Mol Cell Biol. 2006 May;26(9):3492-504. doi: 10.1128/MCB.26.9.3492-3504.2006. Mol Cell Biol. 2006. PMID: 16611991 Free PMC article.

5

The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation.

Basak S, Jacobs SB, Krieg AJ, Pathak N, Zeng Q, Kaldis P, Giaccia AJ, Attardi LD. Basak S, et al. Among authors: giaccia aj. Mol Cell. 2008 May 9;30(3):303-14. doi: 10.1016/j.molcel.2008.04.002. Mol Cell. 2008. PMID: 18471976 Free PMC article.

6

The ever-expanding role of HIF in tumour and stromal biology.

LaGory EL, Giaccia AJ. LaGory EL, et al. Among authors: giaccia aj. Nat Cell Biol. 2016 Apr;18(4):356-65. doi: 10.1038/ncb3330. Nat Cell Biol. 2016. PMID: 27027486 Free PMC article. Review.

7

The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality.

Johnson TM, Hammond EM, Giaccia A, Attardi LD. Johnson TM, et al. Nat Genet. 2005 Feb;37(2):145-52. doi: 10.1038/ng1498. Epub 2005 Jan 16. Nat Genet. 2005. PMID: 15654339

8

Long-range hypoxia signaling in NAFLD.

LaGory EL, Giaccia AJ. LaGory EL, et al. Among authors: giaccia aj. Nat Med. 2017 Nov 7;23(11):1251-1252. doi: 10.1038/nm.4436. Nat Med. 2017. PMID: 29117167 No abstract available.

9

Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia.

Li Y, Gruber JJ, Litzenburger UM, Zhou Y, Miao YR, LaGory EL, Li AM, Hu Z, Yip M, Hart LS, Maris JM, Chang HY, Giaccia AJ, Ye J. Li Y, et al. Among authors: giaccia aj. Cell Death Dis. 2020 Feb 6;11(2):102. doi: 10.1038/s41419-020-2303-9. Cell Death Dis. 2020. PMID: 32029721 Free PMC article.

10

The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling.

Moon EJ, Mello SS, Li CG, Chi JT, Thakkar K, Kirkland JG, Lagory EL, Lee IJ, Diep AN, Miao Y, Rafat M, Vilalta M, Castellini L, Krieg AJ, Graves EE, Attardi LD, Giaccia AJ. Moon EJ, et al. Among authors: giaccia aj. Nat Commun. 2021 Jul 14;12(1):4308. doi: 10.1038/s41467-021-24631-6. Nat Commun. 2021. PMID: 34262028 Free PMC article.

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