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Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity.
Majumder B, Baraneedharan U, Thiyagarajan S, Radhakrishnan P, Narasimhan H, Dhandapani M, Brijwani N, Pinto DD, Prasath A, Shanthappa BU, Thayakumar A, Surendran R, Babu GK, Shenoy AM, Kuriakose MA, Bergthold G, Horowitz P, Loda M, Beroukhim R, Agarwal S, Sengupta S, Sundaram M, Majumder PK. Majumder B, et al. Among authors: thiyagarajan s. Nat Commun. 2015 Feb 27;6:6169. doi: 10.1038/ncomms7169. Nat Commun. 2015. PMID: 25721094 Free PMC article.
Inhibition of rapamycin-induced AKT activation elicits differential antitumor response in head and neck cancers.
Radhakrishnan P, Baraneedharan U, Veluchamy S, Dhandapani M, Pinto DD, Thiyagarajan S, Thayakumar A, Prasath A, A K, Velu A, Jain M, Brijwani N, Narayanan P, Kekatpure VD, Majumder B, Majumder PK. Radhakrishnan P, et al. Among authors: thiyagarajan s. Cancer Res. 2013 Feb 1;73(3):1118-27. doi: 10.1158/0008-5472.CAN-12-2545. Epub 2013 Jan 29. Cancer Res. 2013. PMID: 23361299
Integrating Systems Biology and an Ex Vivo Human Tumor Model Elucidates PD-1 Blockade Response Dynamics.
Smalley M, Przedborski M, Thiyagarajan S, Pellowe M, Verma A, Brijwani N, Datta D, Jain M, Shanthappa BU, Kapoor V, Gopinath KS, Doval DC, Sabitha KS, Taroncher-Oldenburg G, Majumder B, Majumder P, Kohandel M, Goldman A. Smalley M, et al. Among authors: thiyagarajan s. iScience. 2020 Jun 26;23(6):101229. doi: 10.1016/j.isci.2020.101229. Epub 2020 Jun 2. iScience. 2020. PMID: 32554190 Free PMC article.
JAK-STAT inhibitor as a potential therapeutic opportunity in AML patients resistant to cytarabine and epigenetic therapy.
Babu G, Chaudhuri P, Rajappa M, Biswas M, Sansar B, Rajegowda C, Radhakrishnan A, Advani J, Tewary B, Radhakrishnan P, Thiyagarajan S, Chatterjee A, Upadhayaya RS, Majumder PK. Babu G, et al. Among authors: thiyagarajan s. Cancer Biol Ther. 2021 Jan 2;22(1):66-78. doi: 10.1080/15384047.2020.1831371. Epub 2020 Dec 27. Cancer Biol Ther. 2021. PMID: 33356802 Free PMC article.
Phosphoproteomic analysis identifies CLK1 as a novel therapeutic target in gastric cancer.
Babu N, Pinto SM, Biswas M, Subbannayya T, Rajappa M, Mohan SV, Advani J, Rajagopalan P, Sathe G, Syed N, Radhakrishna VD, Muthusamy O, Navani S, Kumar RV, Gopisetty G, Rajkumar T, Radhakrishnan P, Thiyagarajan S, Pandey A, Gowda H, Majumder P, Chatterjee A. Babu N, et al. Among authors: thiyagarajan s. Gastric Cancer. 2020 Sep;23(5):796-810. doi: 10.1007/s10120-020-01062-8. Epub 2020 Apr 24. Gastric Cancer. 2020. PMID: 32333232
Comprehensive network map of interferon gamma signaling.
Bhat MY, Solanki HS, Advani J, Khan AA, Keshava Prasad TS, Gowda H, Thiyagarajan S, Chatterjee A. Bhat MY, et al. Among authors: thiyagarajan s. J Cell Commun Signal. 2018 Dec;12(4):745-751. doi: 10.1007/s12079-018-0486-y. Epub 2018 Sep 6. J Cell Commun Signal. 2018. PMID: 30191398 Free PMC article.
Identification of potential biomarkers of head and neck squamous cell carcinoma using iTRAQ based quantitative proteomic approach.
Babu N, Mohan S, Nanjappa V, Chavan S, Advani J, Khan AA, Renuse S, Radhakrishnan A, Prasad TSK, Kumar RV, Ray JG, Biswas M, Thiyagarajan S, Califano JA, Sidransky D, Gowda H, Chatterjee A. Babu N, et al. Among authors: thiyagarajan s. Data Brief. 2018 May 24;19:1124-1130. doi: 10.1016/j.dib.2018.05.100. eCollection 2018 Aug. Data Brief. 2018. PMID: 30225281 Free PMC article.
Nelfinavir induces radiation sensitization in pituitary adenoma cells.
Zeng J, See AP, Aziz K, Thiyagarajan S, Salih T, Gajula RP, Armour M, Phallen J, Terezakis S, Kleinberg L, Redmond K, Hales RK, Salvatori R, Quinones-Hinojosa A, Tran PT, Lim M. Zeng J, et al. Among authors: thiyagarajan s. Cancer Biol Ther. 2011 Oct 1;12(7):657-63. doi: 10.4161/cbt.12.7.17172. Epub 2011 Oct 1. Cancer Biol Ther. 2011. PMID: 21811091 Free PMC article.
124 results