Youdim MB - Search Results

1

A novel antioxidant multitarget iron chelator M30 protects hepatocytes against ethanol-induced injury.

Xiao J, Lv Y, Lin B, Tipoe GL, Youdim MB, Xing F, Liu Y. Xiao J, et al. Among authors: youdim mb. Oxid Med Cell Longev. 2015;2015:607271. doi: 10.1155/2015/607271. Epub 2015 Feb 4. Oxid Med Cell Longev. 2015. PMID: 25722794 Free PMC article.

2

Iron-Chelating Drugs Enhance Cone Photoreceptor Survival in a Mouse Model of Retinitis Pigmentosa.

Wang K, Peng B, Xiao J, Weinreb O, Youdim MBH, Lin B. Wang K, et al. Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5287-5297. doi: 10.1167/iovs.17-22096. Invest Ophthalmol Vis Sci. 2017. PMID: 29049732

3

The protective, rescue and therapeutic potential of multi-target iron-chelators for retinitis pigmentosa.

Lin B, Youdim MBH. Lin B, et al. Among authors: youdim mbh. Free Radic Biol Med. 2021 Oct;174:1-11. doi: 10.1016/j.freeradbiomed.2021.07.031. Epub 2021 Jul 26. Free Radic Biol Med. 2021. PMID: 34324978 Review.

4

M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus.

Lam CS, Tipoe GL, Wong JK, Youdim MB, Fung ML. Lam CS, et al. Among authors: youdim mb. PLoS One. 2016 Nov 21;11(11):e0166966. doi: 10.1371/journal.pone.0166966. eCollection 2016. PLoS One. 2016. PMID: 27870896 Free PMC article.

5

Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration.

Lam CS, Li JJ, Tipoe GL, Youdim MBH, Fung ML. Lam CS, et al. PLoS One. 2017 Jun 9;12(6):e0177940. doi: 10.1371/journal.pone.0177940. eCollection 2017. PLoS One. 2017. PMID: 28599322 Free PMC article.

6

Inhibition of caspase-9 aggravates acute liver injury through suppression of cytoprotective autophagy.

Guo R, Lin B, Pan JF, Liong EC, Xu AM, Youdim M, Fung ML, So KF, Tipoe GL. Guo R, et al. Sci Rep. 2016 Sep 1;6:32447. doi: 10.1038/srep32447. Sci Rep. 2016. PMID: 27580936 Free PMC article.

7

Up-regulation of hypoxia-inducible factor (HIF)-1α and HIF-target genes in cortical neurons by the novel multifunctional iron chelator anti-Alzheimer drug, M30.

Avramovich-Tirosh Y, Bar-Am O, Amit T, Youdim MB, Weinreb O. Avramovich-Tirosh Y, et al. Among authors: youdim mb. Curr Alzheimer Res. 2010 Jun;7(4):300-6. doi: 10.2174/156720510791162403. Curr Alzheimer Res. 2010. PMID: 20043814

8

Novel molecular targets of the neuroprotective/neurorescue multimodal iron chelating drug M30 in the mouse brain.

Kupershmidt L, Weinreb O, Amit T, Mandel S, Bar-Am O, Youdim MB. Kupershmidt L, et al. Among authors: youdim mb. Neuroscience. 2011 Aug 25;189:345-58. doi: 10.1016/j.neuroscience.2011.03.040. Epub 2011 May 6. Neuroscience. 2011. PMID: 21570450

9

The novel multi-target iron chelator, M30 modulates HIF-1α-related glycolytic genes and insulin signaling pathway in the frontal cortex of APP/PS1 Alzheimer's disease mice.

Mechlovich D, Amit T, Bar-Am O, Mandel S, Youdim MB, Weinreb O. Mechlovich D, et al. Among authors: youdim mb. Curr Alzheimer Res. 2014 Feb;11(2):119-27. doi: 10.2174/1567205010666131212112529. Curr Alzheimer Res. 2014. PMID: 24359498

10

Novel therapeutic approach for neurodegenerative pathologies: multitarget iron-chelating drugs regulating hypoxia-inducible factor 1 signal transduction pathway.

Weinreb O, Amit T, Mandel S, Youdim MB. Weinreb O, et al. Among authors: youdim mb. Neurodegener Dis. 2012;10(1-4):112-5. doi: 10.1159/000332597. Epub 2011 Dec 9. Neurodegener Dis. 2012. PMID: 22156453 Review.

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