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Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Ambrus-Aikelin G, Takeda K, Joetham A, Lazic M, Povero D, Santini AM, Pranadinata R, Johnson CD, McGeough MD, Beasley FC, Stansfield R, McBride C, Trzoss L, Hoffman HM, Feldstein AE, Stafford JA, Veal JM, Bain G, Gelfand EW. Ambrus-Aikelin G, et al. Among authors: trzoss l. Sci Rep. 2023 Nov 16;13(1):20081. doi: 10.1038/s41598-023-47251-0. Sci Rep. 2023. PMID: 37973811 Free PMC article. No abstract available.
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Ambrus-Aikelin G, Takeda K, Joetham A, Lazic M, Povero D, Santini AM, Pranadinata R, Johnson CD, McGeough MD, Beasley FC, Stansfield R, McBride C, Trzoss L, Hoffman HM, Feldstein AE, Stafford JA, Veal JM, Bain G, Gelfand EW. Ambrus-Aikelin G, et al. Among authors: trzoss l. Sci Rep. 2023 Aug 19;13(1):13524. doi: 10.1038/s41598-023-39805-z. Sci Rep. 2023. PMID: 37598239 Free PMC article.
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.
McBride C, Trzoss L, Povero D, Lazic M, Ambrus-Aikelin G, Santini A, Pranadinata R, Bain G, Stansfield R, Stafford JA, Veal J, Takahashi R, Ly J, Chen S, Liu L, Nespi M, Blake R, Katewa A, Kleinheinz T, Sujatha-Bhaskar S, Ramamoorthi N, Sims J, McKenzie B, Chen M, Ultsch M, Johnson M, Murray J, Ciferri C, Staben ST, Townsend MJ, Stivala CE. McBride C, et al. Among authors: trzoss l. J Med Chem. 2022 Nov 10;65(21):14721-14739. doi: 10.1021/acs.jmedchem.2c01250. Epub 2022 Oct 24. J Med Chem. 2022. PMID: 36279149
Advance of Seriniquinone Analogues as Melanoma Agents.
Hammons JC, Trzoss L, Jimenez PC, Hirata AS, Costa-Lotufo LV, La Clair JJ, Fenical W. Hammons JC, et al. Among authors: trzoss l. ACS Med Chem Lett. 2019 Feb 6;10(2):186-190. doi: 10.1021/acsmedchemlett.8b00391. eCollection 2019 Feb 14. ACS Med Chem Lett. 2019. PMID: 30783501 Free PMC article.
A commensal strain of Staphylococcus epidermidis protects against skin neoplasia.
Nakatsuji T, Chen TH, Butcher AM, Trzoss LL, Nam SJ, Shirakawa KT, Zhou W, Oh J, Otto M, Fenical W, Gallo RL. Nakatsuji T, et al. Among authors: trzoss ll. Sci Adv. 2018 Feb 28;4(2):eaao4502. doi: 10.1126/sciadv.aao4502. eCollection 2018 Feb. Sci Adv. 2018. PMID: 29507878 Free PMC article.
Single dish gradient screening of small molecule localization.
Beuzer P, Axelrod J, Trzoss L, Fenical W, Dasari R, Evidente A, Kornienko A, Cang H, La Clair JJ. Beuzer P, et al. Among authors: trzoss l. Org Biomol Chem. 2016 Sep 21;14(35):8241-5. doi: 10.1039/c6ob01418f. Epub 2016 Aug 17. Org Biomol Chem. 2016. PMID: 27530345 Free PMC article.
16 results