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Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle.
Gouspillou G, Scheede-Bergdahl C, Spendiff S, Vuda M, Meehan B, Mlynarski H, Archer-Lahlou E, Sgarioto N, Purves-Smith FM, Konokhova Y, Rak J, Chevalier S, Taivassalo T, Hepple RT, Jagoe RT. Gouspillou G, et al. Among authors: hepple rt. Sci Rep. 2015 Mar 3;5:8717. doi: 10.1038/srep08717. Sci Rep. 2015. PMID: 25732599 Free PMC article.
Mitochondrial Energetics in Skeletal Muscle Are Associated With Leg Power and Cardiorespiratory Fitness in the Study of Muscle, Mobility and Aging.
Mau T, Lui LY, Distefano G, Kramer PA, Ramos SV, Toledo FGS, Santanasto AJ, Shankland EG, Marcinek DJ, Jurczak MJ, Sipula I, Bello FM, Duchowny KA, Molina AJA, Sparks LM, Goodpaster BH, Hepple RT, Kritchevsky SB, Newman AB, Cawthon PM, Cummings SR, Coen PM. Mau T, et al. Among authors: hepple rt. J Gerontol A Biol Sci Med Sci. 2023 Aug 2;78(8):1367-1375. doi: 10.1093/gerona/glac238. J Gerontol A Biol Sci Med Sci. 2023. PMID: 36462195 Free PMC article.
Signatures of cysteine oxidation on muscle structural and contractile proteins are associated with physical performance and muscle function in older adults: Study of Muscle, Mobility and Aging (SOMMA).
Day NJ, Kelly SS, Lui LY, Mansfield TA, Gaffrey MJ, Trejo JB, Sagendorf TJ, Attah IK, Moore RJ, Douglas CM, Newman AB, Kritchevsky SB, Kramer PA, Marcinek DJ, Coen PM, Goodpaster BH, Hepple RT, Cawthon PM, Petyuk VA, Esser KA, Qian WJ, Cummings SR. Day NJ, et al. Among authors: hepple rt. Aging Cell. 2024 Jun;23(6):e14094. doi: 10.1111/acel.14094. Epub 2024 Feb 8. Aging Cell. 2024. PMID: 38332629 Free PMC article.
Associations of Skeletal Muscle Mass, Muscle Fat Infiltration, Mitochondrial Energetics, and Cardiorespiratory Fitness with Liver Fat Among Older Adults.
Igudesman D, Mucinski J, Harrison S, Cawthon PM, Linge J, Goodpaster BH, Cummings SR, Hepple RT, Jurczak MJ, Kritchevsky SB, Marcinek D, Coen PM, Corbin KD. Igudesman D, et al. Among authors: hepple rt. medRxiv [Preprint]. 2023 Oct 25:2023.10.24.23297480. doi: 10.1101/2023.10.24.23297480. medRxiv. 2023. Update in: J Gerontol A Biol Sci Med Sci. 2024 Apr 1;79(4):glae047. doi: 10.1093/gerona/glae047 PMID: 37961367 Free PMC article. Updated. Preprint.
Nutrient Metabolites Associated With Low D3Cr Muscle Mass, Strength, and Physical Performance in Older Men.
Hetherington-Rauth M, Johnson E, Migliavacca E, Parimi N, Langsetmo L, Hepple RT, Grzywinski Y, Corthesy J, Ryan TE, Ferrucci L, Feige JN, Orwoll ES, Cawthon PM. Hetherington-Rauth M, et al. Among authors: hepple rt. J Gerontol A Biol Sci Med Sci. 2024 Feb 1;79(2):glad217. doi: 10.1093/gerona/glad217. J Gerontol A Biol Sci Med Sci. 2024. PMID: 37694554 Free PMC article.
Skeletal Muscle Energetics Explain the Sex Disparity in Mobility Impairment in the Study of Muscle, Mobility and Aging.
Kramer PA, Coen PM, Cawthon PM, Distefano G, Cummings SR, Goodpaster BH, Hepple RT, Kritchevsky SB, Shankland EG, Marcinek DJ, Toledo FGS, Duchowny KA, Ramos SV, Harrison S, Newman AB, Molina AJA. Kramer PA, et al. Among authors: hepple rt. J Gerontol A Biol Sci Med Sci. 2024 Apr 1;79(4):glad283. doi: 10.1093/gerona/glad283. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38150179 Free PMC article.
Role of Cardiorespiratory Fitness and Mitochondrial Energetics in Reduced Walk Speed of Older Adults with Diabetes in the Study of Muscle, Mobility and Aging (SOMMA).
Ramos SV, Distefano G, Lui LY, Cawthon PM, Kramer P, Sipula IJ, Bello FM, Mau T, Jurczak MJ, Molina AJ, Kershaw EE, Marcinek DJ, Toledo FGS, Newman AB, Hepple RT, Kritchevsky SB, Goodpaster BH, Cummings SR, Coen PM. Ramos SV, et al. Among authors: hepple rt. medRxiv [Preprint]. 2023 Nov 6:2023.11.03.23297992. doi: 10.1101/2023.11.03.23297992. medRxiv. 2023. Update in: Diabetes. 2024 Jul 1;73(7):1048-1057. doi: 10.2337/db23-0827 PMID: 37986814 Free PMC article. Updated. Preprint.
Higher Expression of Denervation-responsive Genes is Negatively Associated with Muscle Volume and Performance Traits in the Study of Muscle, Mobility and Aging (SOMMA).
Lukasiewicz CJ, Tranah GJ, Evans DS, Coen PM, Barnes HN, Huo Z, Esser KA, Lane NE, Kritchevsky SB, Newman AB, Cummings SR, Cawthon PM, Hepple RT. Lukasiewicz CJ, et al. Among authors: hepple rt. medRxiv [Preprint]. 2023 Nov 5:2023.11.04.23298090. doi: 10.1101/2023.11.04.23298090. medRxiv. 2023. Update in: Aging Cell. 2024 Jun;23(6):e14115. doi: 10.1111/acel.14115 PMID: 37961531 Free PMC article. Updated. Preprint.
133 results