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eRapa restores a normal life span in a FAP mouse model.
Hasty P, Livi CB, Dodds SG, Jones D, Strong R, Javors M, Fischer KE, Sloane L, Murthy K, Hubbard G, Sun L, Hurez V, Curiel TJ, Sharp ZD. Hasty P, et al. Cancer Prev Res (Phila). 2014 Jan;7(1):169-78. doi: 10.1158/1940-6207.CAPR-13-0299. Epub 2013 Nov 26. Cancer Prev Res (Phila). 2014. PMID: 24282255 Free PMC article.
p53 and rapamycin are additive.
Christy B, Demaria M, Campisi J, Huang J, Jones D, Dodds SG, Williams C, Hubbard G, Livi CB, Gao X, Weintraub S, Curiel T, Sharp ZD, Hasty P. Christy B, et al. Among authors: dodds sg. Oncotarget. 2015 Jun 30;6(18):15802-13. doi: 10.18632/oncotarget.4602. Oncotarget. 2015. PMID: 26158292 Free PMC article.
Adaptations to chronic rapamycin in mice.
Dodds SG, Livi CB, Parihar M, Hsu HK, Benavides AD, Morris J, Javors M, Strong R, Christy B, Hasty P, Sharp ZD. Dodds SG, et al. Pathobiol Aging Age Relat Dis. 2016 May 27;6:31688. doi: 10.3402/pba.v6.31688. eCollection 2016. Pathobiol Aging Age Relat Dis. 2016. PMID: 27237224 Free PMC article.
Acarbose improved survival for Apc+/Min mice.
Dodds SG, Parihar M, Javors M, Nie J, Musi N, Dave Sharp Z, Hasty P. Dodds SG, et al. Aging Cell. 2020 Feb;19(2):e13088. doi: 10.1111/acel.13088. Epub 2020 Jan 6. Aging Cell. 2020. PMID: 31903726 Free PMC article.
277 results