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335 results

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Page 1
Lipotoxicity disrupts incretin-regulated human β cell connectivity.
Hodson DJ, Mitchell RK, Bellomo EA, Sun G, Vinet L, Meda P, Li D, Li WH, Bugliani M, Marchetti P, Bosco D, Piemonti L, Johnson P, Hughes SJ, Rutter GA. Hodson DJ, et al. Among authors: piemonti l. J Clin Invest. 2013 Oct;123(10):4182-94. doi: 10.1172/JCI68459. Epub 2013 Sep 9. J Clin Invest. 2013. PMID: 24018562 Free PMC article.
ADCY5 couples glucose to insulin secretion in human islets.
Hodson DJ, Mitchell RK, Marselli L, Pullen TJ, Gimeno Brias S, Semplici F, Everett KL, Cooper DM, Bugliani M, Marchetti P, Lavallard V, Bosco D, Piemonti L, Johnson PR, Hughes SJ, Li D, Li WH, Shapiro AM, Rutter GA. Hodson DJ, et al. Among authors: piemonti l. Diabetes. 2014 Sep;63(9):3009-21. doi: 10.2337/db13-1607. Epub 2014 Apr 16. Diabetes. 2014. PMID: 24740569 Free PMC article.
Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores.
Marmugi A, Parnis J, Chen X, Carmichael L, Hardy J, Mannan N, Marchetti P, Piemonti L, Bosco D, Johnson P, Shapiro JA, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Thorens B, Valdivia HH, Rutter GA, Leclerc I. Marmugi A, et al. Among authors: piemonti l. Diabetes. 2016 Apr;65(4):1009-21. doi: 10.2337/db15-1334. Epub 2016 Jan 28. Diabetes. 2016. PMID: 26822088 Free PMC article.
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.
Johnston NR, Mitchell RK, Haythorne E, Pessoa MP, Semplici F, Ferrer J, Piemonti L, Marchetti P, Bugliani M, Bosco D, Berishvili E, Duncanson P, Watkinson M, Broichhagen J, Trauner D, Rutter GA, Hodson DJ. Johnston NR, et al. Among authors: piemonti l. Cell Metab. 2016 Sep 13;24(3):389-401. doi: 10.1016/j.cmet.2016.06.020. Epub 2016 Jul 21. Cell Metab. 2016. PMID: 27452146 Free PMC article.
Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.
Fine NHF, Doig CL, Elhassan YS, Vierra NC, Marchetti P, Bugliani M, Nano R, Piemonti L, Rutter GA, Jacobson DA, Lavery GG, Hodson DJ. Fine NHF, et al. Among authors: piemonti l. Diabetes. 2018 Feb;67(2):278-290. doi: 10.2337/db16-1356. Epub 2017 Dec 4. Diabetes. 2018. PMID: 29203512 Free PMC article.
MiR-184 expression is regulated by AMPK in pancreatic islets.
Martinez-Sanchez A, Nguyen-Tu MS, Cebola I, Yavari A, Marchetti P, Piemonti L, de Koning E, Shapiro AMJ, Johnson P, Sakamoto K, Smith DM, Leclerc I, Ashrafian H, Ferrer J, Rutter GA. Martinez-Sanchez A, et al. Among authors: piemonti l. FASEB J. 2018 May;32(5):2587-2600. doi: 10.1096/fj.201701100R. Epub 2018 Jan 8. FASEB J. 2018. PMID: 29269398 Free PMC article.
-S., Cebola, I., Yavari, A., Marchetti, P., Piemonti, L., de Koning, E., Shapiro, A. M. J., Johnson, P., Sakamoto, K., Smith, D. M., Leclerc, I., Ashrafian, H., Ferrer, J., Rutter, G. ...
-S., Cebola, I., Yavari, A., Marchetti, P., Piemonti, L., de Koning, E., Shapiro, A. M. J., Johnson, P., Sakamoto, K., Smith, …
A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells.
Buenaventura T, Kanda N, Douzenis PC, Jones B, Bloom SR, Chabosseau P, Corrêa IR Jr, Bosco D, Piemonti L, Marchetti P, Johnson PR, Shapiro AMJ, Rutter GA, Tomas A. Buenaventura T, et al. Among authors: piemonti l. Diabetes. 2018 Mar;67(3):385-399. doi: 10.2337/db17-0639. Epub 2017 Dec 28. Diabetes. 2018. PMID: 29284659 Free article.
Targeting GLP-1 receptor trafficking to improve agonist efficacy.
Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen BM, Scott R, Goldin R, Angkathunyakul N, Corrêa IR Jr, Bosco D, Johnson PR, Piemonti L, Marchetti P, Shapiro AMJ, Cochran BJ, Hanyaloglu AC, Inoue A, Tan T, Rutter GA, Tomas A, Bloom SR. Jones B, et al. Among authors: piemonti l. Nat Commun. 2018 Apr 23;9(1):1602. doi: 10.1038/s41467-018-03941-2. Nat Commun. 2018. PMID: 29686402 Free PMC article.
The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans.
Izzi-Engbeaya C, Comninos AN, Clarke SA, Jomard A, Yang L, Jones S, Abbara A, Narayanaswamy S, Eng PC, Papadopoulou D, Prague JK, Bech P, Godsland IF, Bassett P, Sands C, Camuzeaux S, Gomez-Romero M, Pearce JTM, Lewis MR, Holmes E, Nicholson JK, Tan T, Ratnasabapathy R, Hu M, Carrat G, Piemonti L, Bugliani M, Marchetti P, Johnson PR, Hughes SJ, James Shapiro AM, Rutter GA, Dhillo WS. Izzi-Engbeaya C, et al. Among authors: piemonti l. Diabetes Obes Metab. 2018 Dec;20(12):2800-2810. doi: 10.1111/dom.13460. Epub 2018 Aug 16. Diabetes Obes Metab. 2018. PMID: 29974637 Free PMC article. Clinical Trial.
335 results