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AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity.
Blair JM, Bavro VN, Ricci V, Modi N, Cacciotto P, Kleinekathӧfer U, Ruggerone P, Vargiu AV, Baylay AJ, Smith HE, Brandon Y, Galloway D, Piddock LJ. Blair JM, et al. Among authors: brandon y. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3511-6. doi: 10.1073/pnas.1419939112. Epub 2015 Mar 3. Proc Natl Acad Sci U S A. 2015. PMID: 25737552 Free PMC article.