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Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.
Shanmughapriya S, Rajan S, Hoffman NE, Zhang X, Guo S, Kolesar JE, Hines KJ, Ragheb J, Jog NR, Caricchio R, Baba Y, Zhou Y, Kaufman BA, Cheung JY, Kurosaki T, Gill DL, Madesh M. Shanmughapriya S, et al. Among authors: madesh m. Sci Signal. 2015 Mar 3;8(366):ra23. doi: 10.1126/scisignal.2005673. Sci Signal. 2015. PMID: 25737585 Free PMC article.
S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.
Hawkins BJ, Irrinki KM, Mallilankaraman K, Lien YC, Wang Y, Bhanumathy CD, Subbiah R, Ritchie MF, Soboloff J, Baba Y, Kurosaki T, Joseph SK, Gill DL, Madesh M. Hawkins BJ, et al. Among authors: madesh m. J Cell Biol. 2010 Aug 9;190(3):391-405. doi: 10.1083/jcb.201004152. Epub 2010 Aug 2. J Cell Biol. 2010. PMID: 20679432 Free PMC article.
Sensing cellular stress through STIM proteins.
Soboloff J, Madesh M, Gill DL. Soboloff J, et al. Among authors: madesh m. Nat Chem Biol. 2011 Jul 18;7(8):488-92. doi: 10.1038/nchembio.619. Nat Chem Biol. 2011. PMID: 21769090 Free PMC article.
Hypoxia-induced acidosis uncouples the STIM-Orai calcium signaling complex.
Mancarella S, Wang Y, Deng X, Landesberg G, Scalia R, Panettieri RA, Mallilankaraman K, Tang XD, Madesh M, Gill DL. Mancarella S, et al. Among authors: madesh m. J Biol Chem. 2011 Dec 30;286(52):44788-98. doi: 10.1074/jbc.M111.303081. Epub 2011 Nov 14. J Biol Chem. 2011. PMID: 22084246 Free PMC article.
STIM proteins: dynamic calcium signal transducers.
Soboloff J, Rothberg BS, Madesh M, Gill DL. Soboloff J, et al. Among authors: madesh m. Nat Rev Mol Cell Biol. 2012 Sep;13(9):549-65. doi: 10.1038/nrm3414. Nat Rev Mol Cell Biol. 2012. PMID: 22914293 Free PMC article. Review.
Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle.
Mancarella S, Potireddy S, Wang Y, Gao H, Gandhirajan RK, Autieri M, Scalia R, Cheng Z, Wang H, Madesh M, Houser SR, Gill DL. Mancarella S, et al. Among authors: madesh m. FASEB J. 2013 Mar;27(3):893-906. doi: 10.1096/fj.12-215293. Epub 2012 Nov 16. FASEB J. 2013. PMID: 23159931 Free PMC article.
-Mancarella, S., Potireddy, S., Wang, Y., Gao, H., Gandhirajan, K., Autieri, M., Scalia, R., Cheng, Z., Wang, H., Madesh, M., Houser, S. R., Gill, D. L. Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle....
-Mancarella, S., Potireddy, S., Wang, Y., Gao, H., Gandhirajan, K., Autieri, M., Scalia, R., Cheng, Z., Wang, H., Madesh, M …
178 results