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Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease.
Lennon R, Stuart HM, Bierzynska A, Randles MJ, Kerr B, Hillman KA, Batra G, Campbell J, Storey H, Flinter FA, Koziell A, Welsh GI, Saleem MA, Webb NJ, Woolf AS. Lennon R, et al. Among authors: welsh gi. Pediatr Nephrol. 2015 Sep;30(9):1459-65. doi: 10.1007/s00467-015-3067-9. Epub 2015 Mar 5. Pediatr Nephrol. 2015. PMID: 25739341 Free PMC article.
The human glomerular podocyte is a novel target for insulin action.
Coward RJ, Welsh GI, Yang J, Tasman C, Lennon R, Koziell A, Satchell S, Holman GD, Kerjaschki D, Tavaré JM, Mathieson PW, Saleem MA. Coward RJ, et al. Among authors: welsh gi. Diabetes. 2005 Nov;54(11):3095-102. doi: 10.2337/diabetes.54.11.3095. Diabetes. 2005. PMID: 16249431
Insulin signaling to the glomerular podocyte is critical for normal kidney function.
Welsh GI, Hale LJ, Eremina V, Jeansson M, Maezawa Y, Lennon R, Pons DA, Owen RJ, Satchell SC, Miles MJ, Caunt CJ, McArdle CA, Pavenstädt H, Tavaré JM, Herzenberg AM, Kahn CR, Mathieson PW, Quaggin SE, Saleem MA, Coward RJM. Welsh GI, et al. Cell Metab. 2010 Oct 6;12(4):329-340. doi: 10.1016/j.cmet.2010.08.015. Cell Metab. 2010. PMID: 20889126 Free PMC article.
138 results