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A Pan-Respiratory Antiviral Chemotype Targeting a Host Multi-Protein Complex.
Michon M, Müller-Schiffmann A, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad MD, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. Michon M, et al. Among authors: crabtree j. bioRxiv [Preprint]. 2023 Dec 12:2021.01.17.426875. doi: 10.1101/2021.01.17.426875. bioRxiv. 2023. Update in: Open Biol. 2024 Jun;14(6):230363. doi: 10.1098/rsob.230363 PMID: 34931190 Free PMC article. Updated. Preprint.
ACE2-IgG1 fusions with improved in vitro and in vivo activity against SARS-CoV-2.
Iwanaga N, Cooper L, Rong L, Maness NJ, Beddingfield B, Qin Z, Crabtree J, Tripp RA, Yang H, Blair R, Jangra S, García-Sastre A, Schotsaert M, Chandra S, Robinson JE, Srivastava A, Rabito F, Qin X, Kolls JK. Iwanaga N, et al. iScience. 2022 Jan 21;25(1):103670. doi: 10.1016/j.isci.2021.103670. Epub 2021 Dec 20. iScience. 2022. PMID: 34957381 Free PMC article.
14 results