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Whole-genome copy-number analysis identifies new leads for chromosomal aberrations involved in the oncogenesis and metastastic behavior of uveal melanomas.
van Engen-van Grunsven AC, Baar MP, Pfundt R, Rijntjes J, Küsters-Vandevelde HV, Delbecq AL, Keunen JE, Klevering JB, Wesseling P, Blokx WA, Groenen PJ. van Engen-van Grunsven AC, et al. Among authors: wesseling p. Melanoma Res. 2015 Jun;25(3):200-9. doi: 10.1097/CMR.0000000000000152. Melanoma Res. 2015. PMID: 25756553
The nature and timing of specific copy number changes in the course of molecular progression in diffuse gliomas: further elucidation of their genetic "life story".
Jeuken JW, Sijben A, Bleeker FE, Boots-Sprenger SH, Rijntjes J, Gijtenbeek JM, Mueller W, Wesseling P. Jeuken JW, et al. Among authors: wesseling p. Brain Pathol. 2011 May;21(3):308-20. doi: 10.1111/j.1750-3639.2010.00447.x. Epub 2010 Nov 3. Brain Pathol. 2011. PMID: 21029244 Free PMC article.
Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.
Pedersen M, Küsters-Vandevelde HVN, Viros A, Groenen PJTA, Sanchez-Laorden B, Gilhuis JH, van Engen-van Grunsven IA, Renier W, Schieving J, Niculescu-Duvaz I, Springer CJ, Küsters B, Wesseling P, Blokx WAM, Marais R. Pedersen M, et al. Among authors: wesseling p. Cancer Discov. 2013 Apr;3(4):458-469. doi: 10.1158/2159-8290.CD-12-0464. Epub 2013 Jan 9. Cancer Discov. 2013. PMID: 23303902 Free PMC article.
Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution.
Boots-Sprenger SH, Sijben A, Rijntjes J, Tops BB, Idema AJ, Rivera AL, Bleeker FE, Gijtenbeek AM, Diefes K, Heathcock L, Aldape KD, Jeuken JW, Wesseling P. Boots-Sprenger SH, et al. Among authors: wesseling p. Mod Pathol. 2013 Jul;26(7):922-9. doi: 10.1038/modpathol.2012.166. Epub 2013 Feb 22. Mod Pathol. 2013. PMID: 23429602 Free article.
Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor.
Küsters-Vandevelde HV, Willemsen AE, Groenen PJ, Küsters B, Lammens M, Wesseling P, Djafarihamedani M, Rijntjes J, Delye H, Willemsen MA, van Herpen CM, Blokx WA. Küsters-Vandevelde HV, et al. Among authors: wesseling p. Acta Neuropathol Commun. 2014 Apr 8;2:41. doi: 10.1186/2051-5960-2-41. Acta Neuropathol Commun. 2014. PMID: 24713450 Free PMC article.
372 results