Winssinger N - Search Results

1

Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules.

Daguer JP, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Daguer JP, et al. Among authors: winssinger n. Angew Chem Int Ed Engl. 2015 May 11;54(20):6057-61. doi: 10.1002/anie.201412276. Epub 2015 Mar 13. Angew Chem Int Ed Engl. 2015. PMID: 25772490

2

Modular asymmetric synthesis of pochonin C.

Barluenga S, Lopez P, Moulin E, Winssinger N. Barluenga S, et al. Among authors: winssinger n. Angew Chem Int Ed Engl. 2004 Jun 28;43(26):3467-70. doi: 10.1002/anie.200454108. Angew Chem Int Ed Engl. 2004. PMID: 15221842 No abstract available.

3

Design, synthesis, and biological evaluation of HSP90 inhibitors based on conformational analysis of radicicol and its analogues.

Moulin E, Zoete V, Barluenga S, Karplus M, Winssinger N. Moulin E, et al. Among authors: winssinger n. J Am Chem Soc. 2005 May 18;127(19):6999-7004. doi: 10.1021/ja043101w. J Am Chem Soc. 2005. PMID: 15884943

4

Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C.

Barluenga S, Moulin E, Lopez P, Winssinger N. Barluenga S, et al. Among authors: winssinger n. Chemistry. 2005 Aug 19;11(17):4935-52. doi: 10.1002/chem.200500160. Chemistry. 2005. PMID: 15940738

5

Concise synthesis of pochonin A, an HSP90 inhibitor.

Moulin E, Barluenga S, Winssinger N. Moulin E, et al. Among authors: winssinger n. Org Lett. 2005 Dec 8;7(25):5637-9. doi: 10.1021/ol052263+. Org Lett. 2005. PMID: 16321010

6

Modular asymmetric synthesis of aigialomycin D, a kinase-inhibitory scaffold.

Barluenga S, Dakas PY, Ferandin Y, Meijer L, Winssinger N. Barluenga S, et al. Among authors: winssinger n. Angew Chem Int Ed Engl. 2006 Jun 12;45(24):3951-4. doi: 10.1002/anie.200600593. Angew Chem Int Ed Engl. 2006. PMID: 16683294 No abstract available.

7

Diversity-oriented synthesis of pochonins and biological evaluation against a panel of kinases.

Moulin E, Barluenga S, Totzke F, Winssinger N. Moulin E, et al. Among authors: winssinger n. Chemistry. 2006 Nov 24;12(34):8819-34. doi: 10.1002/chem.200600553. Chemistry. 2006. PMID: 16953513

8

Chemistry and biology of resorcylic acid lactones.

Winssinger N, Barluenga S. Winssinger N, et al. Chem Commun (Camb). 2007 Jan 7;(1):22-36. doi: 10.1039/b610344h. Epub 2006 Sep 25. Chem Commun (Camb). 2007. PMID: 17279252 Review.

9

Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors.

Dakas PY, Barluenga S, Totzke F, Zirrgiebel U, Winssinger N. Dakas PY, et al. Among authors: winssinger n. Angew Chem Int Ed Engl. 2007;46(36):6899-902. doi: 10.1002/anie.200702406. Angew Chem Int Ed Engl. 2007. PMID: 17676571 No abstract available.

10

Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of an identified inhibitor.

Barluenga S, Wang C, Fontaine JG, Aouadi K, Beebe K, Tsutsumi S, Neckers L, Winssinger N. Barluenga S, et al. Among authors: winssinger n. Angew Chem Int Ed Engl. 2008;47(23):4432-5. doi: 10.1002/anie.200800233. Angew Chem Int Ed Engl. 2008. PMID: 18435518 Free PMC article.

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