Broutin I - Search Results

1

A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling.

Zhang C, Nygaard M, Haxholm GW, Boutillon F, Bernadet M, Hoos S, England P, Broutin I, Kragelund BB, Goffin V. Zhang C, et al. Among authors: broutin i. J Biol Chem. 2015 May 8;290(19):11890-904. doi: 10.1074/jbc.M115.639096. Epub 2015 Mar 17. J Biol Chem. 2015. PMID: 25784554 Free PMC article.

2

Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL.

Jomain JB, Tallet E, Broutin I, Hoos S, van Agthoven J, Ducruix A, Kelly PA, Kragelund BB, England P, Goffin V. Jomain JB, et al. Among authors: broutin i. J Biol Chem. 2007 Nov 9;282(45):33118-31. doi: 10.1074/jbc.M704364200. Epub 2007 Sep 4. J Biol Chem. 2007. PMID: 17785459 Free article.

3

Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.

Broutin I, Jomain JB, Tallet E, van Agthoven J, Raynal B, Hoos S, Kragelund BB, Kelly PA, Ducruix A, England P, Goffin V. Broutin I, et al. J Biol Chem. 2010 Mar 12;285(11):8422-33. doi: 10.1074/jbc.M109.089128. Epub 2010 Jan 6. J Biol Chem. 2010. PMID: 20053995 Free PMC article.

4

Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.

van Agthoven J, Zhang C, Tallet E, Raynal B, Hoos S, Baron B, England P, Goffin V, Broutin I. van Agthoven J, et al. Among authors: broutin i. J Mol Biol. 2010 Nov 19;404(1):112-26. doi: 10.1016/j.jmb.2010.09.036. Epub 2010 Sep 25. J Mol Biol. 2010. PMID: 20875426

5

Residue 146 regulates prolactin receptor folding, basal activity and ligand-responsiveness: potential implications in breast tumorigenesis.

Zhang C, Cherifi I, Nygaard M, Haxholm GW, Bogorad RL, Bernadet M, England P, Broutin I, Kragelund BB, Guidotti JE, Goffin V. Zhang C, et al. Among authors: broutin i. Mol Cell Endocrinol. 2015 Feb 5;401:173-88. doi: 10.1016/j.mce.2014.12.006. Epub 2014 Dec 15. Mol Cell Endocrinol. 2015. PMID: 25524456

6

The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling.

Moncoq K, Broutin I, Larue V, Perdereau D, Cailliau K, Browaeys-Poly E, Burnol AF, Ducruix A. Moncoq K, et al. Among authors: broutin i. FEBS Lett. 2003 Nov 20;554(3):240-6. doi: 10.1016/s0014-5793(03)01095-0. FEBS Lett. 2003. PMID: 14623073 Free article.

7

Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening.

Gautier B, Miteva MA, Goncalves V, Huguenot F, Coric P, Bouaziz S, Seijo B, Gaucher JF, Broutin I, Garbay C, Lesnard A, Rault S, Inguimbert N, Villoutreix BO, Vidal M. Gautier B, et al. Among authors: broutin i. Chem Biol. 2011 Dec 23;18(12):1631-9. doi: 10.1016/j.chembiol.2011.10.016. Chem Biol. 2011. PMID: 22195565

8

Germline Prolactin Receptor Mutation Is Not a Major Cause of Sporadic Prolactinoma in Humans.

Bernard V, Bouilly J, Beau I, Broutin I, Chanson P, Young J, Binart N. Bernard V, et al. Among authors: broutin i. Neuroendocrinology. 2016;103(6):738-45. doi: 10.1159/000442981. Epub 2015 Dec 8. Neuroendocrinology. 2016. PMID: 26641246

9

SAXS study of the PIR domain from the Grb14 molecular adaptor: a natively unfolded protein with a transient structure primer?

Moncoq K, Broutin I, Craescu CT, Vachette P, Ducruix A, Durand D. Moncoq K, et al. Among authors: broutin i. Biophys J. 2004 Dec;87(6):4056-64. doi: 10.1529/biophysj.104.048645. Epub 2004 Oct 1. Biophys J. 2004. PMID: 15465854 Free PMC article.

10

Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis.

le Maire A, Weber T, Saunier S, Broutin I, Antignac C, Ducruix A, Dardel F. le Maire A, et al. Among authors: broutin i. Proteins. 2005 May 1;59(2):347-55. doi: 10.1002/prot.20344. Proteins. 2005. PMID: 15723349

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