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Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.
Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Lopez-Cara C, Schiaffino Ortega S, Brancale A, Hamel E, Castagliuolo I, Mitola S, Ronca R, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: ronca r. J Med Chem. 2015 Apr 9;58(7):3209-22. doi: 10.1021/acs.jmedchem.5b00155. Epub 2015 Mar 26. J Med Chem. 2015. PMID: 25785605 Free PMC article.
The PTX3/TLR4 autocrine loop as a novel therapeutic target in triple negative breast cancer.
Giacomini A, Turati M, Grillo E, Rezzola S, Ghedini GC, Schuind AC, Foglio E, Maccarinelli F, Faletti J, Filiberti S, Chambery A, Valletta M, Melocchi L, Gofflot S, Chiavarina B, Turtoi A, Presta M, Ronca R. Giacomini A, et al. Among authors: ronca r. Exp Hematol Oncol. 2023 Sep 25;12(1):82. doi: 10.1186/s40164-023-00441-y. Exp Hematol Oncol. 2023. PMID: 37749607 Free PMC article.
Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness.
Monti M, Benerini Gatta L, Bugatti M, Pezzali I, Picinoli S, Manfredi M, Lavazza A, Vanella VV, De Giorgis V, Zanatta L, Missale F, Lonardi S, Zanetti B, Bozzoni G, Cadei M, Abate A, Vergani B, Balzarini P, Battocchio S, Facco C, Turri-Zanoni M, Castelnuovo P, Nicolai P, Fonsatti E, Leone BE, Marengo E, Sigala S, Ronca R, Perego M, Lombardi D, Vermi W. Monti M, et al. Among authors: ronca r. J Transl Med. 2024 Jan 8;22(1):35. doi: 10.1186/s12967-023-04784-2. J Transl Med. 2024. PMID: 38191367 Free PMC article.
FGF-trapping hampers cancer stem-like cells in uveal melanoma.
Loda A, Calza S, Giacomini A, Ravelli C, Krishna Chandran AM, Tobia C, Tabellini G, Parolini S, Semeraro F, Ronca R, Rezzola S. Loda A, et al. Among authors: ronca r. Cancer Cell Int. 2023 May 11;23(1):89. doi: 10.1186/s12935-023-02903-z. Cancer Cell Int. 2023. PMID: 37165394 Free PMC article.
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer.
Mahmoud AM, Kostrzewa M, Marolda V, Cerasuolo M, Maccarinelli F, Coltrini D, Rezzola S, Giacomini A, Mollica MP, Motta A, Paris D, Zorzano A, Di Marzo V, Ronca R, Ligresti A. Mahmoud AM, et al. Among authors: ronca r. Pharmacol Res. 2023 Mar;189:106683. doi: 10.1016/j.phrs.2023.106683. Epub 2023 Feb 1. Pharmacol Res. 2023. PMID: 36736415 Free article.
Antiangiogenic activity of semisynthetic biotechnological heparins: low-molecular-weight-sulfated Escherichia coli K5 polysaccharide derivatives as fibroblast growth factor antagonists.
Presta M, Oreste P, Zoppetti G, Belleri M, Tanghetti E, Leali D, Urbinati C, Bugatti A, Ronca R, Nicoli S, Moroni E, Stabile H, Camozzi M, Hernandez GA, Mitola S, Dell'Era P, Rusnati M, Ribatti D. Presta M, et al. Among authors: ronca r. Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):71-6. doi: 10.1161/01.ATV.0000148863.24445.b4. Epub 2004 Oct 28. Arterioscler Thromb Vasc Biol. 2005. PMID: 15514208
Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma.
Faggi F, Chiarelli N, Colombi M, Mitola S, Ronca R, Madaro L, Bouche M, Poliani PL, Vezzoli M, Longhena F, Monti E, Salani B, Maggi D, Keller C, Fanzani A. Faggi F, et al. Among authors: ronca r. Lab Invest. 2015 Jun;95(6):585-602. doi: 10.1038/labinvest.2015.45. Epub 2015 Mar 30. Lab Invest. 2015. PMID: 25822667 Free article.
142 results