Sauer K - Search Results

1

IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice.

Siegemund S, Rigaud S, Conche C, Broaten B, Schaffer L, Westernberg L, Head SR, Sauer K. Siegemund S, et al. Among authors: sauer k. Blood. 2015 Apr 30;125(18):2786-97. doi: 10.1182/blood-2014-06-583187. Epub 2015 Mar 18. Blood. 2015. PMID: 25788703 Free PMC article.

2

Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling.

Sauer K, Park E, Siegemund S, French AR, Wahle JA, Sternberg L, Rigaud S, Jonsson AH, Yokoyama WM, Huang YH. Sauer K, et al. Blood. 2013 Jan 10;121(2):286-97. doi: 10.1182/blood-2012-05-429241. Epub 2012 Nov 21. Blood. 2013. PMID: 23175687 Free PMC article.

3

IP3 3-kinase B prevents bone marrow failure.

Rigaud S, Sauer K. Rigaud S, et al. Among authors: sauer k. Oncotarget. 2015 Jun 30;6(18):15706-7. doi: 10.18632/oncotarget.4480. Oncotarget. 2015. PMID: 26202960 Free PMC article. No abstract available.

4

Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent.

Westernberg L, Conche C, Huang YH, Rigaud S, Deng Y, Siegemund S, Mukherjee S, Nosaka L, Das J, Sauer K. Westernberg L, et al. Among authors: sauer k. Elife. 2016 Feb 11;5:e10786. doi: 10.7554/eLife.10786. Elife. 2016. PMID: 26880557 Free PMC article.

5

Uncovering the PI3Ksome: phosphoinositide 3-kinases and counteracting PTEN form a signaling complex with intrinsic regulatory properties.

Conche C, Sauer K. Conche C, et al. Among authors: sauer k. Mol Cell Biol. 2014 Sep 15;34(18):3356-8. doi: 10.1128/MCB.00920-14. Epub 2014 Jul 21. Mol Cell Biol. 2014. PMID: 25047838 Free PMC article.

6

hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells.

Siegemund S, Shepherd J, Xiao C, Sauer K. Siegemund S, et al. Among authors: sauer k. PLoS One. 2015 Apr 17;10(4):e0124661. doi: 10.1371/journal.pone.0124661. eCollection 2015. PLoS One. 2015. PMID: 25884630 Free PMC article.

7

Protein kinase C η is required for T cell activation and homeostatic proliferation.

Fu G, Hu J, Niederberger-Magnenat N, Rybakin V, Casas J, Yachi PP, Feldstein S, Ma B, Hoerter JA, Ampudia J, Rigaud S, Lambolez F, Gavin AL, Sauer K, Cheroutre H, Gascoigne NR. Fu G, et al. Among authors: sauer k. Sci Signal. 2011 Dec 6;4(202):ra84. doi: 10.1126/scisignal.2002058. Sci Signal. 2011. PMID: 22155788 Free PMC article.

8

Allelic exclusion of TCR α-chains upon severe restriction of Vα repertoire.

Rybakin V, Westernberg L, Fu G, Kim HO, Ampudia J, Sauer K, Gascoigne NR. Rybakin V, et al. Among authors: sauer k. PLoS One. 2014 Dec 12;9(12):e114320. doi: 10.1371/journal.pone.0114320. eCollection 2014. PLoS One. 2014. PMID: 25500569 Free PMC article.

9

Themis sets the signal threshold for positive and negative selection in T-cell development.

Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, Hoerter JA, Paster W, Acuto O, Cheroutre H, Sauer K, Gascoigne NR. Fu G, et al. Among authors: sauer k. Nature. 2013 Dec 19;504(7480):441-5. doi: 10.1038/nature12718. Epub 2013 Nov 13. Nature. 2013. PMID: 24226767 Free PMC article.

10

A conserved motif in the ITK PH-domain is required for phosphoinositide binding and TCR signaling but dispensable for adaptor protein interactions.

Hirve N, Levytskyy RM, Rigaud S, Guimond DM, Zal T, Sauer K, Tsoukas CD. Hirve N, et al. Among authors: sauer k. PLoS One. 2012;7(9):e45158. doi: 10.1371/journal.pone.0045158. Epub 2012 Sep 18. PLoS One. 2012. PMID: 23028816 Free PMC article.

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