Martinez A - Search Results

1

Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3.

Pardo M, King MK, Perez-Costas E, Melendez-Ferro M, Martinez A, Beurel E, Jope RS. Pardo M, et al. Among authors: martinez a. Front Behav Neurosci. 2015 Mar 4;9:55. doi: 10.3389/fnbeh.2015.00055. eCollection 2015. Front Behav Neurosci. 2015. PMID: 25788881 Free PMC article.

2

Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3.

Beurel E, Kaidanovich-Beilin O, Yeh WI, Song L, Palomo V, Michalek SM, Woodgett JR, Harrington LE, Eldar-Finkelman H, Martinez A, Jope RS. Beurel E, et al. Among authors: martinez a. J Immunol. 2013 May 15;190(10):5000-11. doi: 10.4049/jimmunol.1203057. Epub 2013 Apr 19. J Immunol. 2013. PMID: 23606540 Free PMC article.

3

Glycogen synthase kinase-3 inhibitors reverse deficits in long-term potentiation and cognition in fragile X mice.

Franklin AV, King MK, Palomo V, Martinez A, McMahon LL, Jope RS. Franklin AV, et al. Among authors: martinez a. Biol Psychiatry. 2014 Feb 1;75(3):198-206. doi: 10.1016/j.biopsych.2013.08.003. Epub 2013 Sep 13. Biol Psychiatry. 2014. PMID: 24041505 Free PMC article.

4

Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior.

Cheng Y, Pardo M, Armini RS, Martinez A, Mouhsine H, Zagury JF, Jope RS, Beurel E. Cheng Y, et al. Among authors: martinez a. Brain Behav Immun. 2016 Mar;53:207-222. doi: 10.1016/j.bbi.2015.12.012. Epub 2016 Jan 6. Brain Behav Immun. 2016. PMID: 26772151 Free PMC article.

5

Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice.

Pardo M, Cheng Y, Velmeshev D, Magistri M, Eldar-Finkelman H, Martinez A, Faghihi MA, Jope RS, Beurel E. Pardo M, et al. Among authors: martinez a. JCI Insight. 2017 Mar 23;2(6):e91782. doi: 10.1172/jci.insight.91782. JCI Insight. 2017. PMID: 28352664 Free PMC article.

6

TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice.

Cheng Y, Desse S, Martinez A, Worthen RJ, Jope RS, Beurel E. Cheng Y, et al. Among authors: martinez a. Brain Behav Immun. 2018 Mar;69:556-567. doi: 10.1016/j.bbi.2018.02.003. Epub 2018 Feb 13. Brain Behav Immun. 2018. PMID: 29452218 Free PMC article.

7

Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo.

Morales-Garcia JA, Luna-Medina R, Alonso-Gil S, Sanz-Sancristobal M, Palomo V, Gil C, Santos A, Martinez A, Perez-Castillo A. Morales-Garcia JA, et al. Among authors: martinez a. ACS Chem Neurosci. 2012 Nov 21;3(11):963-71. doi: 10.1021/cn300110c. Epub 2012 Sep 24. ACS Chem Neurosci. 2012. PMID: 23173075 Free PMC article.

8

Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders.

Morales-Garcia JA, Palomo V, Redondo M, Alonso-Gil S, Gil C, Martinez A, Perez-Castillo A. Morales-Garcia JA, et al. Among authors: martinez a. ACS Chem Neurosci. 2014 Mar 19;5(3):194-204. doi: 10.1021/cn400166d. Epub 2014 Jan 17. ACS Chem Neurosci. 2014. PMID: 24437940 Free PMC article.

9

Glycogen synthase kinase 3 (GSK-3) inhibitors: a patent update (2014-2015).

Palomo V, Martinez A. Palomo V, et al. Among authors: martinez a. Expert Opin Ther Pat. 2017 Jun;27(6):657-666. doi: 10.1080/13543776.2017.1259412. Epub 2016 Nov 21. Expert Opin Ther Pat. 2017. PMID: 27828716 Free article. Review.

10

Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment.

Martinez A, Gil C, Perez DI. Martinez A, et al. Int J Alzheimers Dis. 2011;2011:280502. doi: 10.4061/2011/280502. Epub 2011 Jun 30. Int J Alzheimers Dis. 2011. PMID: 21760986 Free PMC article.

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