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MITF Modulates Therapeutic Resistance through EGFR Signaling.
Ji Z, Erin Chen Y, Kumar R, Taylor M, Jenny Njauw CN, Miao B, Frederick DT, Wargo JA, Flaherty KT, Jönsson G, Tsao H. Ji Z, et al. Among authors: flaherty kt. J Invest Dermatol. 2015 Jul;135(7):1863-1872. doi: 10.1038/jid.2015.105. Epub 2015 Mar 19. J Invest Dermatol. 2015. PMID: 25789707 Free PMC article.
Molecular therapeutic approaches to melanoma.
Ji Z, Flaherty KT, Tsao H. Ji Z, et al. Among authors: flaherty kt. Mol Aspects Med. 2010 Apr;31(2):194-204. doi: 10.1016/j.mam.2010.02.004. Epub 2010 Feb 20. Mol Aspects Med. 2010. PMID: 20176049 Review.
The farnesyl transferase inhibitor lonafarnib inhibits mTOR signaling and enforces sorafenib-induced apoptosis in melanoma cells.
Niessner H, Beck D, Sinnberg T, Lasithiotakis K, Maczey E, Gogel J, Venturelli S, Berger A, Mauthe M, Toulany M, Flaherty K, Schaller M, Schadendorf D, Proikas-Cezanne T, Schittek B, Garbe C, Kulms D, Meier F. Niessner H, et al. J Invest Dermatol. 2011 Feb;131(2):468-79. doi: 10.1038/jid.2010.297. Epub 2010 Oct 14. J Invest Dermatol. 2011. PMID: 20944654 Free article.
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA. Johannessen CM, et al. Among authors: flaherty kt. Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627. Epub 2010 Nov 24. Nature. 2010. PMID: 21107320 Free PMC article.
Targeting the RAS pathway in melanoma.
Ji Z, Flaherty KT, Tsao H. Ji Z, et al. Among authors: flaherty kt. Trends Mol Med. 2012 Jan;18(1):27-35. doi: 10.1016/j.molmed.2011.08.001. Epub 2011 Sep 30. Trends Mol Med. 2012. PMID: 21962474 Free PMC article. Review.
494 results