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Mechanism of sustained activation of ribosomal S6 kinase (RSK) and ERK by kaposi sarcoma-associated herpesvirus ORF45: multiprotein complexes retain active phosphorylated ERK AND RSK and protect them from dephosphorylation.
Kuang E, Wu F, Zhu F. Kuang E, et al. Among authors: zhu f. J Biol Chem. 2009 May 15;284(20):13958-13968. doi: 10.1074/jbc.M900025200. Epub 2009 Mar 20. J Biol Chem. 2009. PMID: 19304659 Free PMC article.
We have demonstrated previously that the open reading frame 45 (ORF45) of Kaposi sarcoma-associated herpesvirus interacts with p90 ribosomal S6 kinases (RSKs) and strongly stimulates their kinase activities ( Kuang, E., Tang, Q., Maul, G. G., and Zhu, F. (2008) J. V …
We have demonstrated previously that the open reading frame 45 (ORF45) of Kaposi sarcoma-associated herpesvirus interacts with p90 ribosomal …
Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication.
Kuang E, Fu B, Liang Q, Myoung J, Zhu F. Kuang E, et al. Among authors: zhu f. J Biol Chem. 2011 Dec 2;286(48):41171-41182. doi: 10.1074/jbc.M111.280982. Epub 2011 Oct 12. J Biol Chem. 2011. PMID: 21994950 Free PMC article.
8,254 results