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Inter-locus as well as intra-locus heterogeneity in LINE-1 promoter methylation in common human cancers suggests selective demethylation pressure at specific CpGs.
Nüsgen N, Goering W, Dauksa A, Biswas A, Jamil MA, Dimitriou I, Sharma A, Singer H, Fimmers R, Fröhlich H, Oldenburg J, Gulbinas A, Schulz WA, El-Maarri O. Nüsgen N, et al. Among authors: fimmers r. Clin Epigenetics. 2015 Mar 1;7(1):17. doi: 10.1186/s13148-015-0051-y. eCollection 2015. Clin Epigenetics. 2015. PMID: 25798207 Free PMC article.
Methylation of L1Hs promoters is lower on the inactive X, has a tendency of being higher on autosomes in smaller genomes and shows inter-individual variability at some loci.
Singer H, Walier M, Nüsgen N, Meesters C, Schreiner F, Woelfle J, Fimmers R, Wienker T, Kalscheuer VM, Becker T, Schwaab R, Oldenburg J, El-Maarri O. Singer H, et al. Among authors: fimmers r. Hum Mol Genet. 2012 Jan 1;21(1):219-35. doi: 10.1093/hmg/ddr456. Epub 2011 Oct 4. Hum Mol Genet. 2012. PMID: 21972244 Free PMC article.
Tamoxifen induces resistance to activated protein C.
Rühl H, Schröder L, Müller J, Fimmers R, Sukhitashvili S, Welz J, Kuhn WC, Oldenburg J, Rudlowski C, Pötzsch B. Rühl H, et al. Among authors: fimmers r. Thromb Res. 2014 May;133(5):886-91. doi: 10.1016/j.thromres.2014.02.004. Epub 2014 Feb 11. Thromb Res. 2014. PMID: 24568775
Increased circulating levels of neurotrophins and elevated expression of their high-affinity receptors on skin and gut mast cells in mastocytosis.
Peng WM, Maintz L, Allam JP, Raap U, Gütgemann I, Kirfel J, Wardelmann E, Perner S, Zhao W, Fimmers R, Walgenbach K, Oldenburg J, Schwartz LB, Novak N. Peng WM, et al. Among authors: fimmers r. Blood. 2013 Sep 5;122(10):1779-88. doi: 10.1182/blood-2012-12-469882. Epub 2013 Jul 18. Blood. 2013. PMID: 23869086 Free article.
435 results