Stroud RM - Search Results

1

Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.

Salo-Ahen OM, Tochowicz A, Pozzi C, Cardinale D, Ferrari S, Boum Y, Mangani S, Stroud RM, Saxena P, Myllykallio H, Costi MP, Ponterini G, Wade RC. Salo-Ahen OM, et al. Among authors: stroud rm. J Med Chem. 2015 Apr 23;58(8):3572-81. doi: 10.1021/acs.jmedchem.5b00137. Epub 2015 Apr 1. J Med Chem. 2015. PMID: 25798950 Free PMC article.

2

Reversible dissociation and unfolding of the dimeric protein thymidylate synthase.

Perry KM, Pookanjanatavip M, Zhao J, Santi DV, Stroud RM. Perry KM, et al. Among authors: stroud rm. Protein Sci. 1992 Jun;1(6):796-800. doi: 10.1002/pro.5560010611. Protein Sci. 1992. PMID: 1304920 Free PMC article.

3

Crystallization of human thymidylate synthase.

Schiffer CA, Davisson VJ, Santi DV, Stroud RM. Schiffer CA, et al. Among authors: stroud rm. J Mol Biol. 1991 May 20;219(2):161-3. doi: 10.1016/0022-2836(91)90558-n. J Mol Biol. 1991. PMID: 2038053

4

Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases.

Perry KM, Fauman EB, Finer-Moore JS, Montfort WR, Maley GF, Maley F, Stroud RM. Perry KM, et al. Among authors: stroud rm. Proteins. 1990;8(4):315-33. doi: 10.1002/prot.340080406. Proteins. 1990. PMID: 2128651

5

Saturation site-directed mutagenesis of thymidylate synthase.

Climie S, Ruiz-Perez L, Gonzalez-Pacanowska D, Prapunwattana P, Cho SW, Stroud R, Santi DV. Climie S, et al. J Biol Chem. 1990 Nov 5;265(31):18776-9. J Biol Chem. 1990. PMID: 2229040 Free article.

6

Structure-based discovery of inhibitors of thymidylate synthase.

Shoichet BK, Stroud RM, Santi DV, Kuntz ID, Perry KM. Shoichet BK, et al. Among authors: stroud rm. Science. 1993 Mar 5;259(5100):1445-50. doi: 10.1126/science.8451640. Science. 1993. PMID: 8451640

7

The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition.

Stout TJ, Stroud RM. Stout TJ, et al. Among authors: stroud rm. Structure. 1996 Jan 15;4(1):67-77. doi: 10.1016/s0969-2126(96)00010-x. Structure. 1996. PMID: 8805515 Free article.

8

A new class of HIV-1 protease inhibitor: the crystallographic structure, inhibition and chemical synthesis of an aminimide peptide isostere.

Rutenber EE, McPhee F, Kaplan AP, Gallion SL, Hogan JC Jr, Craik CS, Stroud RM. Rutenber EE, et al. Among authors: stroud rm. Bioorg Med Chem. 1996 Sep;4(9):1545-58. doi: 10.1016/0968-0896(96)00147-2. Bioorg Med Chem. 1996. PMID: 8894111

9

Binding of the anticancer drug ZD1694 to E. coli thymidylate synthase: assessing specificity and affinity.

Rutenber EE, Stroud RM. Rutenber EE, et al. Among authors: stroud rm. Structure. 1996 Nov 15;4(11):1317-24. doi: 10.1016/s0969-2126(96)00139-6. Structure. 1996. PMID: 8939755 Free article.

10

An essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58Q.

Sage CR, Rutenber EE, Stout TJ, Stroud RM. Sage CR, et al. Among authors: stroud rm. Biochemistry. 1996 Dec 17;35(50):16270-81. doi: 10.1021/bi961269r. Biochemistry. 1996. PMID: 8973201

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

402 results

Search Page

Filters