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African Swine Fever Virus Georgia Isolate Harboring Deletions of MGF360 and MGF505 Genes Is Attenuated in Swine and Confers Protection against Challenge with Virulent Parental Virus.
O'Donnell V, Holinka LG, Gladue DP, Sanford B, Krug PW, Lu X, Arzt J, Reese B, Carrillo C, Risatti GR, Borca MV. O'Donnell V, et al. Among authors: holinka lg. J Virol. 2015 Jun;89(11):6048-56. doi: 10.1128/JVI.00554-15. Epub 2015 Mar 25. J Virol. 2015. PMID: 25810553 Free PMC article.
Identification of an NTPase motif in classical swine fever virus NS4B protein.
Gladue DP, Gavrilov BK, Holinka LG, Fernandez-Sainz IJ, Vepkhvadze NG, Rogers K, O'Donnell V, Risatti GR, Borca MV. Gladue DP, et al. Among authors: holinka lg. Virology. 2011 Mar 1;411(1):41-9. doi: 10.1016/j.virol.2010.12.028. Epub 2011 Jan 13. Virology. 2011. PMID: 21236462 Free article.
Classical swine fever virus p7 protein is a viroporin involved in virulence in swine.
Gladue DP, Holinka LG, Largo E, Fernandez Sainz I, Carrillo C, O'Donnell V, Baker-Branstetter R, Lu Z, Ambroggio X, Risatti GR, Nieva JL, Borca MV. Gladue DP, et al. Among authors: holinka lg. J Virol. 2012 Jun;86(12):6778-91. doi: 10.1128/JVI.00560-12. Epub 2012 Apr 11. J Virol. 2012. PMID: 22496228 Free PMC article.
The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major modifications of the viral genome.
Krug PW, Holinka LG, O'Donnell V, Reese B, Sanford B, Fernandez-Sainz I, Gladue DP, Arzt J, Rodriguez L, Risatti GR, Borca MV. Krug PW, et al. Among authors: holinka lg. J Virol. 2015 Feb;89(4):2324-32. doi: 10.1128/JVI.03250-14. Epub 2014 Dec 10. J Virol. 2015. PMID: 25505073 Free PMC article.
African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation in Swine and Induces an Effective Protection against Homologous Challenge.
O'Donnell V, Holinka LG, Krug PW, Gladue DP, Carlson J, Sanford B, Alfano M, Kramer E, Lu Z, Arzt J, Reese B, Carrillo C, Risatti GR, Borca MV. O'Donnell V, et al. Among authors: holinka lg. J Virol. 2015 Aug;89(16):8556-66. doi: 10.1128/JVI.00969-15. Epub 2015 Jun 10. J Virol. 2015. PMID: 26063424 Free PMC article.
52 results