Leopoldo M - Search Results

1

Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics.

Speranza L, Giuliano T, Volpicelli F, De Stefano ME, Lombardi L, Chambery A, Lacivita E, Leopoldo M, Bellenchi GC, di Porzio U, Crispino M, Perrone-Capano C. Speranza L, et al. Among authors: leopoldo m. Front Behav Neurosci. 2015 Mar 11;9:62. doi: 10.3389/fnbeh.2015.00062. eCollection 2015. Front Behav Neurosci. 2015. PMID: 25814944 Free PMC article.

2

Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.

Perrone R, Berardi F, Colabufo NA, Lacivita E, Leopoldo M, Tortorella V. Perrone R, et al. Among authors: leopoldo m. J Med Chem. 2003 Feb 13;46(4):646-9. doi: 10.1021/jm020994z. J Med Chem. 2003. PMID: 12570387

3

Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.

Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Perrone R, Tortorella V. Leopoldo M, et al. J Pharm Pharmacol. 2004 Feb;56(2):247-55. doi: 10.1211/0022357022575. J Pharm Pharmacol. 2004. PMID: 15005884

4

First structure-activity relationship study on dopamine D3 receptor agents with N-[4-(4-arylpiperazin-1-yl)butyl]arylcarboxamide structure.

Leopoldo M, Lacivita E, Colabufo NA, Contino M, Berardi F, Perrone R. Leopoldo M, et al. J Med Chem. 2005 Dec 15;48(25):7919-22. doi: 10.1021/jm050729o. J Med Chem. 2005. PMID: 16335915

5

Synthesis and binding profile of constrained analogues of N-[4-(4-arylpiperazin-1-yl)butyl]-3-methoxybenzamides, a class of potent dopamine D3 receptor ligands.

Leopoldo M, Lacivita E, Colabufo NA, Berardi F, Perrone R. Leopoldo M, et al. J Pharm Pharmacol. 2006 Feb;58(2):209-18. doi: 10.1211/jpp.58.2.0008. J Pharm Pharmacol. 2006. PMID: 16451749

6

Selective agents for serotonin2C (5-HT2C) receptor.

Lacivita E, Leopoldo M. Lacivita E, et al. Among authors: leopoldo m. Curr Top Med Chem. 2006;6(18):1927-70. doi: 10.2174/156802606778522168. Curr Top Med Chem. 2006. PMID: 17017967 Review.

7

Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: synthesis and binding affinities for 5-HT(7) and 5-HT(1A) receptors.

Leopoldo M, Lacivita E, Colabufo NA, Niso M, Berardi F, Perrone R. Leopoldo M, et al. Bioorg Med Chem. 2007 Aug 1;15(15):5316-21. doi: 10.1016/j.bmc.2007.05.010. Epub 2007 May 6. Bioorg Med Chem. 2007. PMID: 17517509

8

Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.

Leopoldo M, Lacivita E, Contino M, Colabufo NA, Berardi F, Perrone R. Leopoldo M, et al. J Med Chem. 2007 Aug 23;50(17):4214-21. doi: 10.1021/jm070487n. Epub 2007 Jul 25. J Med Chem. 2007. PMID: 17649988

9

N-[omega-[4-(2-methoxyphenyl)-1-piperazinyl]alkyl]-2-quinolinamines as high-affinity fluorescent 5-HT1A receptor ligands.

Lacivita E, Leopoldo M. Lacivita E, et al. Among authors: leopoldo m. J Med Chem. 2008 Mar 13;51(5):1492-5. doi: 10.1021/jm7013919. Epub 2008 Feb 13. J Med Chem. 2008. PMID: 18269229

10

5-HT1A receptor, an old target for new therapeutic agents.

Lacivita E, Leopoldo M, Berardi F, Perrone R. Lacivita E, et al. Among authors: leopoldo m. Curr Top Med Chem. 2008;8(12):1024-34. doi: 10.2174/156802608785161385. Curr Top Med Chem. 2008. PMID: 18691130 Review.

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