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13,133 results

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Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo.
Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, Talpaz M, Bixby DL, Sun D, Hess JL, Muntean AG, Maillard I, Cierpicki T, Grembecka J. Borkin D, et al. Among authors: sun d. Cancer Cell. 2015 Apr 13;27(4):589-602. doi: 10.1016/j.ccell.2015.02.016. Epub 2015 Mar 26. Cancer Cell. 2015. PMID: 25817203 Free PMC article.
A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo.
Abulwerdi F, Liao C, Liu M, Azmi AS, Aboukameel A, Mady AS, Gulappa T, Cierpicki T, Owens S, Zhang T, Sun D, Stuckey JA, Mohammad RM, Nikolovska-Coleska Z. Abulwerdi F, et al. Among authors: sun d. Mol Cancer Ther. 2014 Mar;13(3):565-75. doi: 10.1158/1535-7163.MCT-12-0767. Epub 2013 Sep 9. Mol Cancer Ther. 2014. PMID: 24019208 Free PMC article.
The role of HTS in drug discovery at the University of Michigan.
Larsen MJ, Larsen SD, Fribley A, Grembecka J, Homan K, Mapp A, Haak A, Nikolovska-Coleska Z, Stuckey JA, Sun D, Sherman DH. Larsen MJ, et al. Among authors: sun d. Comb Chem High Throughput Screen. 2014 Mar;17(3):210-30. doi: 10.2174/1386207317666140109121546. Comb Chem High Throughput Screen. 2014. PMID: 24409957 Free PMC article. Review.
Antineoplastic drug exposure in an ambulatory setting: a pilot study.
Friese CR, McArdle C, Zhao T, Sun D, Spasojevic I, Polovich M, McCullagh MC. Friese CR, et al. Among authors: sun d. Cancer Nurs. 2015 Mar-Apr;38(2):111-7. doi: 10.1097/NCC.0000000000000143. Cancer Nurs. 2015. PMID: 24831047 Free PMC article.
Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein-Protein Interaction between Menin and Mixed Lineage Leukemia (MLL).
Borkin D, Pollock J, Kempinska K, Purohit T, Li X, Wen B, Zhao T, Miao H, Shukla S, He M, Sun D, Cierpicki T, Grembecka J. Borkin D, et al. Among authors: sun d. J Med Chem. 2016 Feb 11;59(3):892-913. doi: 10.1021/acs.jmedchem.5b01305. Epub 2016 Jan 25. J Med Chem. 2016. PMID: 26744767 Free PMC article.
Anti-infective Activity of 2-Cyano-3-Acrylamide Inhibitors with Improved Drug-Like Properties against Two Intracellular Pathogens.
Passalacqua KD, Charbonneau ME, Donato NJ, Showalter HD, Sun D, Wen B, He M, Sun H, O'Riordan MX, Wobus CE. Passalacqua KD, et al. Among authors: sun d, sun h. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4183-96. doi: 10.1128/AAC.03021-15. Print 2016 Jul. Antimicrob Agents Chemother. 2016. PMID: 27139470 Free PMC article.
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