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7,463 results

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Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys.
Ortega-Molina A, Lopez-Guadamillas E, Mattison JA, Mitchell SJ, Muñoz-Martin M, Iglesias G, Gutierrez VM, Vaughan KL, Szarowicz MD, González-García I, López M, Cebrián D, Martinez S, Pastor J, de Cabo R, Serrano M. Ortega-Molina A, et al. Among authors: lopez guadamillas e, lopez m. Cell Metab. 2015 Apr 7;21(4):558-70. doi: 10.1016/j.cmet.2015.02.017. Epub 2015 Mar 26. Cell Metab. 2015. PMID: 25817535 Free PMC article.
Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.
López M, Lage R, Saha AK, Pérez-Tilve D, Vázquez MJ, Varela L, Sangiao-Alvarellos S, Tovar S, Raghay K, Rodríguez-Cuenca S, Deoliveira RM, Castañeda T, Datta R, Dong JZ, Culler M, Sleeman MW, Alvarez CV, Gallego R, Lelliott CJ, Carling D, Tschöp MH, Diéguez C, Vidal-Puig A. López M, et al. Cell Metab. 2008 May;7(5):389-99. doi: 10.1016/j.cmet.2008.03.006. Cell Metab. 2008. PMID: 18460330 Free article.
The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats.
Díaz-Arteaga A, Vázquez MJ, Vazquez-Martínez R, Pulido MR, Suarez J, Velásquez DA, López M, Ross RA, de Fonseca FR, Bermudez-Silva FJ, Malagón MM, Diéguez C, Nogueiras R. Díaz-Arteaga A, et al. Among authors: lopez m. Diabetes Obes Metab. 2012 Mar;14(3):234-43. doi: 10.1111/j.1463-1326.2011.01515.x. Epub 2011 Nov 7. Diabetes Obes Metab. 2012. PMID: 21981246
Ghrelin requires p53 to stimulate lipid storage in fat and liver.
Porteiro B, Díaz-Ruíz A, Martínez G, Senra A, Vidal A, Serrano M, Gualillo O, López M, Malagón MM, Diéguez C, Nogueiras R. Porteiro B, et al. Among authors: lopez m. Endocrinology. 2013 Oct;154(10):3671-9. doi: 10.1210/en.2013-1176. Epub 2013 Jul 5. Endocrinology. 2013. PMID: 23832961
Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK.
Martínez de Morentin PB, González-García I, Martins L, Lage R, Fernández-Mallo D, Martínez-Sánchez N, Ruíz-Pino F, Liu J, Morgan DA, Pinilla L, Gallego R, Saha AK, Kalsbeek A, Fliers E, Bisschop PH, Diéguez C, Nogueiras R, Rahmouni K, Tena-Sempere M, López M. Martínez de Morentin PB, et al. Among authors: lopez m. Cell Metab. 2014 Jul 1;20(1):41-53. doi: 10.1016/j.cmet.2014.03.031. Epub 2014 May 22. Cell Metab. 2014. PMID: 24856932 Free PMC article.
Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance.
Contreras C, González-García I, Martínez-Sánchez N, Seoane-Collazo P, Jacas J, Morgan DA, Serra D, Gallego R, Gonzalez F, Casals N, Nogueiras R, Rahmouni K, Diéguez C, López M. Contreras C, et al. Among authors: lopez m. Cell Rep. 2014 Oct 9;9(1):366-377. doi: 10.1016/j.celrep.2014.08.057. Epub 2014 Oct 2. Cell Rep. 2014. PMID: 25284795 Free PMC article.
Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats.
Martínez de Morentin PB, Lage R, González-García I, Ruíz-Pino F, Martins L, Fernández-Mallo D, Gallego R, Fernø J, Señarís R, Saha AK, Tovar S, Diéguez C, Nogueiras R, Tena-Sempere M, López M. Martínez de Morentin PB, et al. Among authors: lopez m. Endocrinology. 2015 Mar;156(3):947-60. doi: 10.1210/en.2014-1611. Epub 2014 Dec 23. Endocrinology. 2015. PMID: 25535827 Free PMC article.
7,463 results