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27 results

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Page 1
Mitochondrial DNA damage by bleomycin induces AML cell death.
Yeung M, Hurren R, Nemr C, Wang X, Hershenfeld S, Gronda M, Liyanage S, Wu Y, Augustine J, Lee EA, Spagnuolo PA, Southall N, Chen C, Zheng W, Jeyaraju DV, Minden MD, Laposa R, Schimmer AD. Yeung M, et al. Among authors: laposa r. Apoptosis. 2015 Jun;20(6):811-20. doi: 10.1007/s10495-015-1119-z. Apoptosis. 2015. PMID: 25820141
Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML.
Liyanage SU, Hurren R, Voisin V, Bridon G, Wang X, Xu C, MacLean N, Siriwardena TP, Gronda M, Yehudai D, Sriskanthadevan S, Avizonis D, Shamas-Din A, Minden MD, Bader GD, Laposa R, Schimmer AD. Liyanage SU, et al. Among authors: laposa r. Blood. 2017 May 11;129(19):2657-2666. doi: 10.1182/blood-2016-10-741207. Epub 2017 Mar 10. Blood. 2017. PMID: 28283480 Free PMC article.
Targeting mitochondrial RNA polymerase in acute myeloid leukemia.
Bralha FN, Liyanage SU, Hurren R, Wang X, Son MH, Fung TA, Chingcuanco FB, Tung AY, Andreazza AC, Psarianos P, Schimmer AD, Salmena L, Laposa RR. Bralha FN, et al. Among authors: laposa rr. Oncotarget. 2015 Nov 10;6(35):37216-28. doi: 10.18632/oncotarget.6129. Oncotarget. 2015. PMID: 26484416 Free PMC article.
Targeting mitochondrial DNA with a platinum-based anticancer agent.
Wisnovsky SP, Wilson JJ, Radford RJ, Pereira MP, Chan MR, Laposa RR, Lippard SJ, Kelley SO. Wisnovsky SP, et al. Among authors: laposa rr. Chem Biol. 2013 Nov 21;20(11):1323-8. doi: 10.1016/j.chembiol.2013.08.010. Epub 2013 Oct 31. Chem Biol. 2013. PMID: 24183971 Free PMC article.
DNA Polymerase θ Increases Mutational Rates in Mitochondrial DNA.
Wisnovsky S, Sack T, Pagliarini DJ, Laposa RR, Kelley SO. Wisnovsky S, et al. Among authors: laposa rr. ACS Chem Biol. 2018 Apr 20;13(4):900-908. doi: 10.1021/acschembio.8b00072. Epub 2018 Mar 15. ACS Chem Biol. 2018. PMID: 29509408 Free PMC article.
Cockayne syndrome b maintains neural precursor function.
Sacco R, Tamblyn L, Rajakulendran N, Bralha FN, Tropepe V, Laposa RR. Sacco R, et al. Among authors: laposa rr. DNA Repair (Amst). 2013 Feb 1;12(2):110-20. doi: 10.1016/j.dnarep.2012.11.004. Epub 2012 Dec 11. DNA Repair (Amst). 2013. PMID: 23245699
Oxidative damage in chemical teratogenesis.
Wells PG, Kim PM, Laposa RR, Nicol CJ, Parman T, Winn LM. Wells PG, et al. Among authors: laposa rr. Mutat Res. 1997 Dec 12;396(1-2):65-78. doi: 10.1016/s0027-5107(97)00175-9. Mutat Res. 1997. PMID: 9434860 Review.
Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species.
Wells PG, Bhuller Y, Chen CS, Jeng W, Kasapinovic S, Kennedy JC, Kim PM, Laposa RR, McCallum GP, Nicol CJ, Parman T, Wiley MJ, Wong AW. Wells PG, et al. Among authors: laposa rr. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):354-66. doi: 10.1016/j.taap.2005.01.061. Toxicol Appl Pharmacol. 2005. PMID: 16081118 Review.
27 results