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LMNA Mutation c.917T>G (p.L306R) Leads to Deleterious Hyper-Assembly of Lamin A/C and Associates with Severe Right Ventricular Cardiomyopathy and Premature Aging.
Alastalo TP, West G, Li SP, Keinänen A, Helenius M, Tyni T, Lapatto R, Turanlahti M, Heikkilä P, Kääriäinen H, Laakso M, Mauermann M, Herrmann H, Pihkala J, Taimen P. Alastalo TP, et al. Among authors: helenius m. Hum Mutat. 2015 Jul;36(7):694-703. doi: 10.1002/humu.22793. Epub 2015 Jun 1. Hum Mutat. 2015. PMID: 25820511
Extracellular ATP protects endothelial cells against DNA damage.
Aho J, Helenius M, Vattulainen-Collanus S, Alastalo TP, Koskenvuo J. Aho J, et al. Among authors: helenius m. Purinergic Signal. 2016 Sep;12(3):575-81. doi: 10.1007/s11302-016-9508-5. Epub 2016 Mar 31. Purinergic Signal. 2016. PMID: 27030122 Free PMC article.
Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension.
Helenius MH, Vattulainen S, Orcholski M, Aho J, Komulainen A, Taimen P, Wang L, de Jesus Perez VA, Koskenvuo JW, Alastalo TP. Helenius MH, et al. Am J Physiol Lung Cell Mol Physiol. 2015 May 15;308(10):L1046-57. doi: 10.1152/ajplung.00340.2014. Epub 2015 Mar 27. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25820525 Free article. Clinical Trial.
Systemic Dosing of Thymosin Beta 4 before and after Ischemia Does Not Attenuate Global Myocardial Ischemia-Reperfusion Injury in Pigs.
Stark CK, Tarkia M, Kentala R, Malmberg M, Vähäsilta T, Savo M, Hynninen VV, Helenius M, Ruohonen S, Jalkanen J, Taimen P, Alastalo TP, Saraste A, Knuuti J, Savunen T, Koskenvuo J. Stark CK, et al. Among authors: helenius m. Front Pharmacol. 2016 May 3;7:115. doi: 10.3389/fphar.2016.00115. eCollection 2016. Front Pharmacol. 2016. PMID: 27199757 Free PMC article.
Endothelial cells cope with hypoxia-induced depletion of ATP via activation of cellular purine turnover and phosphotransfer networks.
Losenkova K, Zuccarini M, Helenius M, Jacquemet G, Gerasimovskaya E, Tallgren C, Jalkanen S, Yegutkin GG. Losenkova K, et al. Among authors: helenius m. Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1804-1815. doi: 10.1016/j.bbadis.2018.03.001. Epub 2018 Mar 4. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29514048 Free article.
Enhancing the abscopal effect of radiation and immune checkpoint inhibitor therapies with magnetic nanoparticle hyperthermia in a model of metastatic breast cancer.
Oei AL, Korangath P, Mulka K, Helenius M, Coulter JB, Stewart J, Velarde E, Crezee J, Simons B, Stalpers LJA, Kok HP, Gabrielson K, Franken NAP, Ivkov R. Oei AL, et al. Among authors: helenius m. Int J Hyperthermia. 2019 Nov;36(sup1):47-63. doi: 10.1080/02656736.2019.1685686. Int J Hyperthermia. 2019. PMID: 31795835 Free PMC article.
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