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Page 1
High-content analysis of kinase activity in cells.
Gasparri F, Sola F, Bandiera T, Moll J, Galvani A. Gasparri F, et al. Among authors: moll j. Comb Chem High Throughput Screen. 2008 Aug;11(7):523-36. doi: 10.2174/138620708785204126. Comb Chem High Throughput Screen. 2008. PMID: 18694389 Review.
PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.
Soncini C, Carpinelli P, Gianellini L, Fancelli D, Vianello P, Rusconi L, Storici P, Zugnoni P, Pesenti E, Croci V, Ceruti R, Giorgini ML, Cappella P, Ballinari D, Sola F, Varasi M, Bravo R, Moll J. Soncini C, et al. Among authors: moll j. Clin Cancer Res. 2006 Jul 1;12(13):4080-9. doi: 10.1158/1078-0432.CCR-05-1964. Clin Cancer Res. 2006. PMID: 16818708
NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies.
Valsasina B, Beria I, Alli C, Alzani R, Avanzi N, Ballinari D, Cappella P, Caruso M, Casolaro A, Ciavolella A, Cucchi U, De Ponti A, Felder E, Fiorentini F, Galvani A, Gianellini LM, Giorgini ML, Isacchi A, Lansen J, Pesenti E, Rizzi S, Rocchetti M, Sola F, Moll J. Valsasina B, et al. Among authors: moll j. Mol Cancer Ther. 2012 Apr;11(4):1006-16. doi: 10.1158/1535-7163.MCT-11-0765. Epub 2012 Feb 7. Mol Cancer Ther. 2012. PMID: 22319201
Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors.
Beria I, Ballinari D, Bertrand JA, Borghi D, Bossi RT, Brasca MG, Cappella P, Caruso M, Ceccarelli W, Ciavolella A, Cristiani C, Croci V, De Ponti A, Fachin G, Ferguson RD, Lansen J, Moll JK, Pesenti E, Posteri H, Perego R, Rocchetti M, Storici P, Volpi D, Valsasina B. Beria I, et al. Among authors: moll jk. J Med Chem. 2010 May 13;53(9):3532-51. doi: 10.1021/jm901713n. J Med Chem. 2010. PMID: 20397705
PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer.
Carpinelli P, Ceruti R, Giorgini ML, Cappella P, Gianellini L, Croci V, Degrassi A, Texido G, Rocchetti M, Vianello P, Rusconi L, Storici P, Zugnoni P, Arrigoni C, Soncini C, Alli C, Patton V, Marsiglio A, Ballinari D, Pesenti E, Fancelli D, Moll J. Carpinelli P, et al. Among authors: moll j. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3158-68. doi: 10.1158/1535-7163.MCT-07-0444. Mol Cancer Ther. 2007. PMID: 18089710
844 results