Moran DM - Search Results

1

Structural and functional screening in human induced-pluripotent stem cell-derived cardiomyocytes accurately identifies cardiotoxicity of multiple drug types.

Doherty KR, Talbert DR, Trusk PB, Moran DM, Shell SA, Bacus S. Doherty KR, et al. Among authors: moran dm. Toxicol Appl Pharmacol. 2015 May 15;285(1):51-60. doi: 10.1016/j.taap.2015.03.008. Epub 2015 Apr 2. Toxicol Appl Pharmacol. 2015. PMID: 25841593

2

Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes.

Doherty KR, Wappel RL, Talbert DR, Trusk PB, Moran DM, Kramer JW, Brown AM, Shell SA, Bacus S. Doherty KR, et al. Among authors: moran dm. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):245-55. doi: 10.1016/j.taap.2013.04.027. Epub 2013 May 21. Toxicol Appl Pharmacol. 2013. PMID: 23707608

3

A multi-parameter in vitro screen in human stem cell-derived cardiomyocytes identifies ponatinib-induced structural and functional cardiac toxicity.

Talbert DR, Doherty KR, Trusk PB, Moran DM, Shell SA, Bacus S. Talbert DR, et al. Among authors: moran dm. Toxicol Sci. 2015 Jan;143(1):147-55. doi: 10.1093/toxsci/kfu215. Epub 2014 Oct 10. Toxicol Sci. 2015. PMID: 25304212

4

KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells.

Moran DM, Trusk PB, Pry K, Paz K, Sidransky D, Bacus SS. Moran DM, et al. Mol Cancer Ther. 2014 Jun;13(6):1611-24. doi: 10.1158/1535-7163.MCT-13-0649. Epub 2014 Mar 31. Mol Cancer Ther. 2014. PMID: 24688052

5

Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors.

Hamm CA, Moran D, Rao K, Trusk PB, Pry K, Sausen M, Jones S, Velculescu VE, Cristofanilli M, Bacus S. Hamm CA, et al. Mol Cancer Ther. 2016 Jul;15(7):1746-56. doi: 10.1158/1535-7163.MCT-15-0353. Epub 2016 Apr 19. Mol Cancer Ther. 2016. PMID: 27196778

6

Nutlin-3a induces cytoskeletal rearrangement and inhibits the migration and invasion capacity of p53 wild-type cancer cells.

Moran DM, Maki CG. Moran DM, et al. Mol Cancer Ther. 2010 Apr;9(4):895-905. doi: 10.1158/1535-7163.MCT-09-1220. Epub 2010 Apr 6. Mol Cancer Ther. 2010. PMID: 20371712 Free PMC article.

7

A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non-small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations.

Yu HA, Spira A, Horn L, Weiss J, West H, Giaccone G, Evans T, Kelly RJ, Desai B, Krivoshik A, Moran D, Poondru S, Jie F, Aoyama K, Keating A, Oxnard GR. Yu HA, et al. Clin Cancer Res. 2017 Dec 15;23(24):7467-7473. doi: 10.1158/1078-0432.CCR-17-1447. Epub 2017 Sep 27. Clin Cancer Res. 2017. PMID: 28954786 Free PMC article. Clinical Trial.

8

Transient nutlin-3a treatment promotes endoreduplication and the generation of therapy-resistant tetraploid cells.

Shen H, Moran DM, Maki CG. Shen H, et al. Among authors: moran dm. Cancer Res. 2008 Oct 15;68(20):8260-8. doi: 10.1158/0008-5472.CAN-08-1901. Cancer Res. 2008. PMID: 18922897 Free PMC article.

9

Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells.

Moran DM, Gawlak G, Jayaprakash MS, Mayar S, Maki CG. Moran DM, et al. Oncogene. 2008 Sep 18;27(42):5567-77. doi: 10.1038/onc.2008.172. Epub 2008 May 26. Oncogene. 2008. PMID: 18504430 Free PMC article.

10

Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors.

Breen MJ, Moran DM, Liu W, Huang X, Vary CP, Bergan RC. Breen MJ, et al. Among authors: moran dm. PLoS One. 2013 Aug 13;8(8):e72407. doi: 10.1371/journal.pone.0072407. eCollection 2013. PLoS One. 2013. PMID: 23967299 Free PMC article.

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