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An evaluation of the utility of LVdP/dt40, QA interval, LVdP/dtmin and Tau as indicators of drug-induced changes in contractility and lusitropy in dogs.
Pugsley MK, Guth B, Chiang AY, Doyle JM, Engwall M, Guillon JM, Hoffmann PK, Koerner JE, Mittelstadt SW, Pierson JB, Rossman EI, Sarazan DR, Parish ST. Pugsley MK, et al. J Pharmacol Toxicol Methods. 2017 May-Jun;85:1-21. doi: 10.1016/j.vascn.2017.01.002. Epub 2017 Jan 5. J Pharmacol Toxicol Methods. 2017. PMID: 28065821 Free article.
Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation.
Rossman EI, Cools F, Cordes J, Dhuyvetter D, Doyle JM, Friedrichs GS, Guth B, Neradilek MB, Parish ST, Pierson JB, Polissar N, Tang HM. Rossman EI, et al. J Pharmacol Toxicol Methods. 2020 Sep;105:106897. doi: 10.1016/j.vascn.2020.106897. Epub 2020 Jul 12. J Pharmacol Toxicol Methods. 2020. PMID: 32663523
Drug safety Africa: An overview of safety pharmacology & toxicology in South Africa.
Guth BD, Grobler AF, Frazier KS, Greiter-Wilke A, Herzyk D, Hough TA, Khan AA, Markert M, Smith JD, Svenson KL, Wells S, Pugsley MK. Guth BD, et al. J Pharmacol Toxicol Methods. 2019 Jul-Aug;98:106579. doi: 10.1016/j.vascn.2019.106579. Epub 2019 May 11. J Pharmacol Toxicol Methods. 2019. PMID: 31085319 Free article. Review.
Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms.
Guth BD, Engwall M, Eldridge S, Foley CM, Guo L, Gintant G, Koerner J, Parish ST, Pierson JB, Ribeiro AJS, Zabka T, Chaudhary KW, Kanda Y, Berridge B. Guth BD, et al. Front Pharmacol. 2019 Aug 9;10:884. doi: 10.3389/fphar.2019.00884. eCollection 2019. Front Pharmacol. 2019. PMID: 31447679 Free PMC article. Review.
Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes.
Ribeiro AJS, Guth BD, Engwall M, Eldridge S, Foley CM, Guo L, Gintant G, Koerner J, Parish ST, Pierson JB, Brock M, Chaudhary KW, Kanda Y, Berridge B. Ribeiro AJS, et al. Among authors: guth bd. Front Pharmacol. 2019 Aug 29;10:934. doi: 10.3389/fphar.2019.00934. eCollection 2019. Front Pharmacol. 2019. PMID: 31555128 Free PMC article. Review.
115 results