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ITI-007 demonstrates brain occupancy at serotonin 5-HT₂A and dopamine D₂ receptors and serotonin transporters using positron emission tomography in healthy volunteers.
Davis RE, Vanover KE, Zhou Y, Brašić JR, Guevara M, Bisuna B, Ye W, Raymont V, Willis W, Kumar A, Gapasin L, Goldwater DR, Mates S, Wong DF. Davis RE, et al. Among authors: kumar a. Psychopharmacology (Berl). 2015 Aug;232(15):2863-72. doi: 10.1007/s00213-015-3922-1. Epub 2015 Apr 7. Psychopharmacology (Berl). 2015. PMID: 25843749 Free article.
Sex differences in striatal dopamine release in healthy adults.
Munro CA, McCaul ME, Wong DF, Oswald LM, Zhou Y, Brasic J, Kuwabara H, Kumar A, Alexander M, Ye W, Wand GS. Munro CA, et al. Among authors: kumar a. Biol Psychiatry. 2006 May 15;59(10):966-74. doi: 10.1016/j.biopsych.2006.01.008. Epub 2006 Apr 17. Biol Psychiatry. 2006. PMID: 16616726 Clinical Trial.
Striatal dopamine release and family history of alcoholism.
Munro CA, McCaul ME, Oswald LM, Wong DF, Zhou Y, Brasic J, Kuwabara H, Kumar A, Alexander M, Ye W, Wand GS. Munro CA, et al. Among authors: kumar a. Alcohol Clin Exp Res. 2006 Jul;30(7):1143-51. doi: 10.1111/j.1530-0277.2006.00130.x. Alcohol Clin Exp Res. 2006. PMID: 16792561
Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET.
Wong DF, Brasić JR, Singer HS, Schretlen DJ, Kuwabara H, Zhou Y, Nandi A, Maris MA, Alexander M, Ye W, Rousset O, Kumar A, Szabo Z, Gjedde A, Grace AA. Wong DF, et al. Among authors: kumar a. Neuropsychopharmacology. 2008 May;33(6):1239-51. doi: 10.1038/sj.npp.1301528. Epub 2007 Nov 7. Neuropsychopharmacology. 2008. PMID: 17987065 Free PMC article. Clinical Trial.
Cognition and amyloid load in Alzheimer disease imaged with florbetapir F 18(AV-45) positron emission tomography.
Rosenberg PB, Wong DF, Edell SL, Ross JS, Joshi AD, Brašić JR, Zhou Y, Raymont V, Kumar A, Ravert HT, Dannals RF, Pontecorvo MJ, Skovronsky DM, Lyketsos CG. Rosenberg PB, et al. Among authors: kumar a. Am J Geriatr Psychiatry. 2013 Mar;21(3):272-8. doi: 10.1016/j.jagp.2012.11.016. Am J Geriatr Psychiatry. 2013. PMID: 23395194 Free PMC article.
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving.
Wong DF, Kuwabara H, Schretlen DJ, Bonson KR, Zhou Y, Nandi A, Brasić JR, Kimes AS, Maris MA, Kumar A, Contoreggi C, Links J, Ernst M, Rousset O, Zukin S, Grace AA, Lee JS, Rohde C, Jasinski DR, Gjedde A, London ED. Wong DF, et al. Among authors: kumar a. Neuropsychopharmacology. 2006 Dec;31(12):2716-27. doi: 10.1038/sj.npp.1301194. Epub 2006 Sep 13. Neuropsychopharmacology. 2006. PMID: 16971900
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