Scozzafava A - Search Results

1

Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.

Bozdag M, Carta F, Vullo D, Akdemir A, Isik S, Lanzi C, Scozzafava A, Masini E, Supuran CT. Bozdag M, et al. Among authors: scozzafava a. Bioorg Med Chem. 2015 May 15;23(10):2368-76. doi: 10.1016/j.bmc.2015.03.068. Epub 2015 Mar 31. Bioorg Med Chem. 2015. PMID: 25846066

2

Carbonic anhydrase activators: high affinity isozymes I, II, and IV activators, incorporating a beta-alanyl-histidine scaffold.

Scozzafava A, Supuran CT. Scozzafava A, et al. J Med Chem. 2002 Jan 17;45(2):284-91. doi: 10.1021/jm010958k. J Med Chem. 2002. PMID: 11784133

3

Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties.

Masereel B, Rolin S, Abbate F, Scozzafava A, Supuran CT. Masereel B, et al. Among authors: scozzafava a. J Med Chem. 2002 Jan 17;45(2):312-20. doi: 10.1021/jm0109199. J Med Chem. 2002. PMID: 11784136

4

Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.

Scozzafava A, Menabuoni L, Mincione F, Supuran CT. Scozzafava A, et al. J Med Chem. 2002 Mar 28;45(7):1466-76. doi: 10.1021/jm0108202. J Med Chem. 2002. PMID: 11906288

5

Carbonic anhydrase activators: human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1.

Scozzafava A, Supuran CT. Scozzafava A, et al. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1177-80. doi: 10.1016/s0960-894x(02)00121-x. Bioorg Med Chem Lett. 2002. PMID: 11934582

6

Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.

Scozzafava A, Supuran CT. Scozzafava A, et al. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1551-7. doi: 10.1016/s0960-894x(02)00252-4. Bioorg Med Chem Lett. 2002. PMID: 12039560

7

Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design.

Abbate F, Supuran CT, Scozzafava A, Orioli P, Stubbs MT, Klebe G. Abbate F, et al. Among authors: scozzafava a. J Med Chem. 2002 Aug 15;45(17):3583-7. doi: 10.1021/jm011131t. J Med Chem. 2002. PMID: 12166931

8

Protease inhibitors: synthesis of matrix metalloproteinase and bacterial collagenase inhibitors incorporating 5-amino-2-mercapto-1,3,4-thiadiazole zinc binding functions.

Scozzafava A, Supuran CT. Scozzafava A, et al. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2667-72. doi: 10.1016/s0960-894x(02)00564-4. Bioorg Med Chem Lett. 2002. PMID: 12217351

9

Carbonic anhydrase inhibitors with strong topical antiglaucoma properties incorporating a 4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide scaffold.

Casini A, Mincione F, Vullo D, Menabuoni L, Scozzafava A, Supuran CT. Casini A, et al. Among authors: scozzafava a. J Enzyme Inhib Med Chem. 2002 Feb;17(1):9-18. doi: 10.1080/14756360290018602. J Enzyme Inhib Med Chem. 2002. PMID: 12365464 Free article.

10

Carbonic anhydrase inhibitors.

Supuran CT, Scozzafava A, Casini A. Supuran CT, et al. Among authors: scozzafava a. Med Res Rev. 2003 Mar;23(2):146-89. doi: 10.1002/med.10025. Med Res Rev. 2003. PMID: 12500287 Review.

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