Walsh DM - Search Results

1

The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species.

Mc Donald JM, O'Malley TT, Liu W, Mably AJ, Brinkmalm G, Portelius E, Wittbold WM 3rd, Frosch MP, Walsh DM. Mc Donald JM, et al. Among authors: walsh dm. Alzheimers Dement. 2015 Nov;11(11):1286-305. doi: 10.1016/j.jalz.2015.01.005. Epub 2015 Apr 4. Alzheimers Dement. 2015. PMID: 25846299 Free PMC article.

2

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.

Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. Sharon R, et al. Among authors: walsh dm. Neuron. 2003 Feb 20;37(4):583-95. doi: 10.1016/s0896-6273(03)00024-2. Neuron. 2003. PMID: 12597857 Free article.

3

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ. Leissring MA, et al. Among authors: walsh dm. Neuron. 2003 Dec 18;40(6):1087-93. doi: 10.1016/s0896-6273(03)00787-6. Neuron. 2003. PMID: 14687544 Free article.

4

A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease.

Xia W, Yang T, Shankar G, Smith IM, Shen Y, Walsh DM, Selkoe DJ. Xia W, et al. Among authors: walsh dm. Arch Neurol. 2009 Feb;66(2):190-9. doi: 10.1001/archneurol.2008.565. Arch Neurol. 2009. PMID: 19204155 Free PMC article.

5

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life.

Shankar GM, Leissring MA, Adame A, Sun X, Spooner E, Masliah E, Selkoe DJ, Lemere CA, Walsh DM. Shankar GM, et al. Among authors: walsh dm. Neurobiol Dis. 2009 Nov;36(2):293-302. doi: 10.1016/j.nbd.2009.07.021. Epub 2009 Aug 4. Neurobiol Dis. 2009. PMID: 19660551 Free PMC article.

6

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

Mc Donald JM, Savva GM, Brayne C, Welzel AT, Forster G, Shankar GM, Selkoe DJ, Ince PG, Walsh DM; Medical Research Council Cognitive Function and Ageing Study. Mc Donald JM, et al. Among authors: walsh dm. Brain. 2010 May;133(Pt 5):1328-41. doi: 10.1093/brain/awq065. Epub 2010 Apr 19. Brain. 2010. PMID: 20403962 Free PMC article.

7

Isolation of low-n amyloid β-protein oligomers from cultured cells, CSF, and brain.

Shankar GM, Welzel AT, McDonald JM, Selkoe DJ, Walsh DM. Shankar GM, et al. Among authors: walsh dm. Methods Mol Biol. 2011;670:33-44. doi: 10.1007/978-1-60761-744-0_3. Methods Mol Biol. 2011. PMID: 20967581

8

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration.

Jin M, Shepardson N, Yang T, Chen G, Walsh D, Selkoe DJ. Jin M, et al. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5819-24. doi: 10.1073/pnas.1017033108. Epub 2011 Mar 18. Proc Natl Acad Sci U S A. 2011. PMID: 21421841 Free PMC article.

9

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.

Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, Wüllner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Kumar S, et al. Among authors: walsh dm. EMBO J. 2011 Jun 1;30(11):2255-65. doi: 10.1038/emboj.2011.138. Epub 2011 Apr 28. EMBO J. 2011. PMID: 21527912 Free PMC article.

10

Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein.

Barry AE, Klyubin I, Mc Donald JM, Mably AJ, Farrell MA, Scott M, Walsh DM, Rowan MJ. Barry AE, et al. Among authors: walsh dm. J Neurosci. 2011 May 18;31(20):7259-63. doi: 10.1523/JNEUROSCI.6500-10.2011. J Neurosci. 2011. PMID: 21593310 Free PMC article.

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