Gobec S - Search Results

1

Furan-based benzene mono- and dicarboxylic acid derivatives as multiple inhibitors of the bacterial Mur ligases (MurC-MurF): experimental and computational characterization.

Perdih A, Hrast M, Pureber K, Barreteau H, Grdadolnik SG, Kocjan D, Gobec S, Solmajer T, Wolber G. Perdih A, et al. Among authors: gobec s. J Comput Aided Mol Des. 2015 Jun;29(6):541-60. doi: 10.1007/s10822-015-9843-6. Epub 2015 Apr 8. J Comput Aided Mol Des. 2015. PMID: 25851408

2

Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD.

Strancar K, Blanot D, Gobec S. Strancar K, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2006 Jan 15;16(2):343-8. doi: 10.1016/j.bmcl.2005.09.086. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16271472

3

Flavonoids and cinnamic acid esters as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase: a synthesis, QSAR and modelling study.

Sova M, Perdih A, Kotnik M, Kristan K, Rizner TL, Solmajer T, Gobec S. Sova M, et al. Among authors: gobec s. Bioorg Med Chem. 2006 Nov 15;14(22):7404-18. doi: 10.1016/j.bmc.2006.07.027. Epub 2006 Aug 7. Bioorg Med Chem. 2006. PMID: 16891119

4

Diazenedicarboxamides as inhibitors of D-alanine-D-alanine ligase (Ddl).

Kovac A, Majce V, Lenarsic R, Bombek S, Bostock JM, Chopra I, Polanc S, Gobec S. Kovac A, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2047-54. doi: 10.1016/j.bmcl.2007.01.015. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17267218

5

Phosphinate inhibitors of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: L-lysine ligase (MurE).

Strancar K, Boniface A, Blanot D, Gobec S. Strancar K, et al. Among authors: gobec s. Arch Pharm (Weinheim). 2007 Mar;340(3):127-34. doi: 10.1002/ardp.200600191. Arch Pharm (Weinheim). 2007. PMID: 17335103

6

Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase.

Kotnik M, Humljan J, Contreras-Martel C, Oblak M, Kristan K, Hervé M, Blanot D, Urleb U, Gobec S, Dessen A, Solmajer T. Kotnik M, et al. Among authors: gobec s. J Mol Biol. 2007 Jun 29;370(1):107-15. doi: 10.1016/j.jmb.2007.04.048. Epub 2007 May 4. J Mol Biol. 2007. PMID: 17507028

7

Cytoplasmic steps of peptidoglycan biosynthesis.

Barreteau H, Kovac A, Boniface A, Sova M, Gobec S, Blanot D. Barreteau H, et al. Among authors: gobec s. FEMS Microbiol Rev. 2008 Mar;32(2):168-207. doi: 10.1111/j.1574-6976.2008.00104.x. Epub 2008 Feb 11. FEMS Microbiol Rev. 2008. PMID: 18266853 Free article. Review.

8

Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases.

Sink R, Kovac A, Tomasić T, Rupnik V, Boniface A, Bostock J, Chopra I, Blanot D, Masic LP, Gobec S, Zega A. Sink R, et al. Among authors: gobec s. ChemMedChem. 2008 Sep;3(9):1362-70. doi: 10.1002/cmdc.200800087. ChemMedChem. 2008. PMID: 18651694

9

Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.

Humljan J, Kotnik M, Contreras-Martel C, Blanot D, Urleb U, Dessen A, Solmajer T, Gobec S. Humljan J, et al. Among authors: gobec s. J Med Chem. 2008 Dec 11;51(23):7486-94. doi: 10.1021/jm800762u. J Med Chem. 2008. PMID: 19007109

10

Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase.

Tomasić T, Zidar N, Rupnik V, Kovac A, Blanot D, Gobec S, Kikelj D, Masic LP. Tomasić T, et al. Among authors: gobec s. Bioorg Med Chem Lett. 2009 Jan 1;19(1):153-7. doi: 10.1016/j.bmcl.2008.10.129. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19014883

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