Singh SB - Search Results

1

Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2).

Singh SB, Kaelin DE, Wu J, Miesel L, Tan CM, Black T, Nargund R, Meinke PT, Olsen DB, Lagrutta A, Lu J, Patel S, Rickert KW, Smith RF, Soisson S, Sherer E, Joyce LA, Wei C, Peng X, Wang X, Fukuda H, Kishii R, Takei M, Takano H, Shibasaki M, Yajima M, Nishimura A, Shibata T, Fukuda Y. Singh SB, et al. Bioorg Med Chem Lett. 2015 May 1;25(9):1831-5. doi: 10.1016/j.bmcl.2015.03.044. Epub 2015 Mar 24. Bioorg Med Chem Lett. 2015. PMID: 25851938

2

Ophiobolin M and analogues, noncompetitive inhibitors of ivermectin binding with nematocidal activity.

Tsipouras A, Adefarati AA, Tkacz JS, Frazier EG, Rohrer SP, Birzin E, Rosegay A, Zink DL, Goetz MA, Singh SB, Schaeffer JM. Tsipouras A, et al. Among authors: singh sb. Bioorg Med Chem. 1996 Apr;4(4):531-6. doi: 10.1016/0968-0896(96)00036-3. Bioorg Med Chem. 1996. PMID: 8735840

3

Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.

Darkin-Rattray SJ, Gurnett AM, Myers RW, Dulski PM, Crumley TM, Allocco JJ, Cannova C, Meinke PT, Colletti SL, Bednarek MA, Singh SB, Goetz MA, Dombrowski AW, Polishook JD, Schmatz DM. Darkin-Rattray SJ, et al. Among authors: singh sb. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13143-7. doi: 10.1073/pnas.93.23.13143. Proc Natl Acad Sci U S A. 1996. PMID: 8917558 Free PMC article.

4

Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.

Lingham RB, Silverman KC, Jayasuriya H, Kim BM, Amo SE, Wilson FR, Rew DJ, Schaber MD, Bergstrom JD, Koblan KS, Graham SL, Kohl NE, Gibbs JB, Singh SB. Lingham RB, et al. Among authors: singh sb. J Med Chem. 1998 Nov 5;41(23):4492-501. doi: 10.1021/jm980356+. J Med Chem. 1998. PMID: 9804689

5

Kampanols: novel Ras farnesyl-protein transferase inhibitors from Stachybotrys kampalensis.

Singh SB, Zink DL, Williams M, Polishook JD, Sanchez M, Silverman KC, Lingham RB. Singh SB, et al. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2071-6. doi: 10.1016/s0960-894x(98)00371-0. Bioorg Med Chem Lett. 1998. PMID: 9873488

6

Coprophilin: an anticoccidial agent produced by a dung inhabiting fungus.

Ondeyka JG, Giacobbe RA, Bills GF, Cuadrillero C, Schmatz D, Goetz MA, Zink DL, Singh SB. Ondeyka JG, et al. Among authors: singh sb. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3439-42. doi: 10.1016/s0960-894x(98)00629-5. Bioorg Med Chem Lett. 1998. PMID: 9934448

7

Chemical and enzymatic modifications of integric acid and HIV-1 integrase inhibitory activity.

Singh SB, Felock P, Hazuda DJ. Singh SB, et al. Bioorg Med Chem Lett. 2000 Feb 7;10(3):235-8. doi: 10.1016/s0960-894x(99)00666-6. Bioorg Med Chem Lett. 2000. PMID: 10698443

8

Efficient syntheses, human and yeast farnesyl-protein transferase inhibitory activities of chaetomellic acids and analogues.

Singh SB, Jayasuriya H, Silverman KC, Bonfiglio CA, Williamson JM, Lingham RB. Singh SB, et al. Bioorg Med Chem. 2000 Mar;8(3):571-80. doi: 10.1016/s0968-0896(99)00312-0. Bioorg Med Chem. 2000. PMID: 10732974

9

Tetrahydroisoquinoline derivatives containing a benzenesulfonamide moiety as potent, selective human beta3 adrenergic receptor agonists.

Parmee ER, Brockunier LL, He J, Singh SB, Candelore MR, Cascieri MA, Deng L, Liu Y, Tota L, Wyvratt MJ, Fisher MH, Weber AE. Parmee ER, et al. Among authors: singh sb. Bioorg Med Chem Lett. 2000 Oct 16;10(20):2283-6. doi: 10.1016/s0960-894x(00)00459-5. Bioorg Med Chem Lett. 2000. PMID: 11055339

10

Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues.

Singh SB, Graham PL, Reamer RA, Cordingley MG. Singh SB, et al. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3143-6. doi: 10.1016/s0960-894x(01)00648-5. Bioorg Med Chem Lett. 2001. PMID: 11720861

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