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Page 1
Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2).
Singh SB, Kaelin DE, Wu J, Miesel L, Tan CM, Black T, Nargund R, Meinke PT, Olsen DB, Lagrutta A, Lu J, Patel S, Rickert KW, Smith RF, Soisson S, Sherer E, Joyce LA, Wei C, Peng X, Wang X, Fukuda H, Kishii R, Takei M, Takano H, Shibasaki M, Yajima M, Nishimura A, Shibata T, Fukuda Y. Singh SB, et al. Among authors: yajima m. Bioorg Med Chem Lett. 2015 May 1;25(9):1831-5. doi: 10.1016/j.bmcl.2015.03.044. Epub 2015 Mar 24. Bioorg Med Chem Lett. 2015. PMID: 25851938
Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6).
Singh SB, Kaelin DE, Wu J, Miesel L, Tan CM, Meinke PT, Olsen DB, Lagrutta A, Wei C, Liao Y, Peng X, Wang X, Fukuda H, Kishii R, Takei M, Yajima M, Shibue T, Shibata T, Ohata K, Nishimura A, Fukuda Y. Singh SB, et al. Among authors: yajima m. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3636-43. doi: 10.1016/j.bmcl.2015.06.057. Epub 2015 Jun 19. Bioorg Med Chem Lett. 2015. PMID: 26141771
Discovery of Novel Bicyclic Pyrazoles as Potent PIP5K1C Inhibitors.
Ochiai K, Seto S, Yajima M, Namie R, Hashimoto N, Fujita M, Yokoyama A, Suezawa T, Matsui H, Tomizawa S, Ishibashi Y, Tanaka Y, Yajima M, Nagasawa M, Ando N. Ochiai K, et al. Among authors: yajima m. ACS Med Chem Lett. 2024 Apr 3;15(5):684-690. doi: 10.1021/acsmedchemlett.4c00090. eCollection 2024 May 9. ACS Med Chem Lett. 2024. PMID: 38746884
Human iPSC-liver organoid transplantation reduces fibrosis through immunomodulation.
Tadokoro T, Murata S, Kato M, Ueno Y, Tsuchida T, Okumura A, Kuse Y, Konno T, Uchida Y, Yamakawa Y, Zushi M, Yajima M, Kobayashi T, Hasegawa S, Kawakatsu-Hatada Y, Hayashi Y, Osakabe S, Maeda T, Kimura K, Mori A, Tanaka M, Kamishibahara Y, Matsuo M, Nie YZ, Okamoto S, Oba T, Tanimizu N, Taniguchi H. Tadokoro T, et al. Among authors: yajima m. Sci Transl Med. 2024 Jul 24;16(757):eadg0338. doi: 10.1126/scitranslmed.adg0338. Epub 2024 Jul 24. Sci Transl Med. 2024. PMID: 39047116
330 results