Wan X - Search Results

1

Phosphorylation of mutationally introduced tyrosine in the activation loop of HER2 confers gain-of-function activity.

Hu Z, Wan X, Hao R, Zhang H, Li L, Li L, Xie Q, Wang P, Gao Y, Chen S, Wei M, Luan Z, Zhang A, Huang N, Chen L. Hu Z, et al. Among authors: wan x. PLoS One. 2015 Apr 8;10(4):e0123623. doi: 10.1371/journal.pone.0123623. eCollection 2015. PLoS One. 2015. PMID: 25853726 Free PMC article.

2

A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling.

Wan X, Zhang W, Li L, Xie Y, Li W, Huang N. Wan X, et al. J Med Chem. 2013 Mar 28;56(6):2619-29. doi: 10.1021/jm400045y. Epub 2013 Mar 15. J Med Chem. 2013. PMID: 23442188

3

Ab initio modeling and experimental assessment of Janus Kinase 2 (JAK2) kinase-pseudokinase complex structure.

Wan X, Ma Y, McClendon CL, Huang LJ, Huang N. Wan X, et al. PLoS Comput Biol. 2013 Apr;9(4):e1003022. doi: 10.1371/journal.pcbi.1003022. Epub 2013 Apr 4. PLoS Comput Biol. 2013. PMID: 23592968 Free PMC article.

4

Structure and specificity of the bacterial cysteine methyltransferase effector NleE suggests a novel substrate in human DNA repair pathway.

Yao Q, Zhang L, Wan X, Chen J, Hu L, Ding X, Li L, Karar J, Peng H, Chen S, Huang N, Rauscher FJ 3rd, Shao F. Yao Q, et al. Among authors: wan x. PLoS Pathog. 2014 Nov 20;10(11):e1004522. doi: 10.1371/journal.ppat.1004522. eCollection 2014 Nov. PLoS Pathog. 2014. PMID: 25412445 Free PMC article.

5

Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.

Yao Q, Cui J, Wang J, Li T, Wan X, Luo T, Gong YN, Xu Y, Huang N, Shao F. Yao Q, et al. Among authors: wan x. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20395-400. doi: 10.1073/pnas.1210831109. Epub 2012 Nov 21. Proc Natl Acad Sci U S A. 2012. PMID: 23175788 Free PMC article.

6

Discovery of Novel Pim-1 Kinase Inhibitors with a Flexible-Receptor Docking Protocol.

Li G, Li W, Xie Y, Wan X, Zheng G, Huang N, Zhou Y. Li G, et al. Among authors: wan x. J Chem Inf Model. 2019 Oct 28;59(10):4116-4119. doi: 10.1021/acs.jcim.9b00494. Epub 2019 Oct 17. J Chem Inf Model. 2019. PMID: 31609618

7

A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family.

Yao Q, Lu Q, Wan X, Song F, Xu Y, Hu M, Zamyatina A, Liu X, Huang N, Zhu P, Shao F. Yao Q, et al. Among authors: wan x. Elife. 2014 Oct 13;3:e03714. doi: 10.7554/eLife.03714. Elife. 2014. PMID: 25310236 Free PMC article.

8

Molecular determinants of enterovirus 71 viral entry: cleft around GLN-172 on VP1 protein interacts with variable region on scavenge receptor B 2.

Chen P, Song Z, Qi Y, Feng X, Xu N, Sun Y, Wu X, Yao X, Mao Q, Li X, Dong W, Wan X, Huang N, Shen X, Liang Z, Li W. Chen P, et al. Among authors: wan x. J Biol Chem. 2012 Feb 24;287(9):6406-20. doi: 10.1074/jbc.M111.301622. Epub 2012 Jan 4. J Biol Chem. 2012. PMID: 22219187 Free PMC article.

9

Characterization of a Unique Pathway for 4-Cresol Catabolism Initiated by Phosphorylation in Corynebacterium glutamicum.

Du L, Ma L, Qi F, Zheng X, Jiang C, Li A, Wan X, Liu SJ, Li S. Du L, et al. Among authors: wan x. J Biol Chem. 2016 Mar 18;291(12):6583-94. doi: 10.1074/jbc.M115.695320. Epub 2016 Jan 27. J Biol Chem. 2016. PMID: 26817843 Free PMC article.

10

Selective oxidation of aliphatic C-H bonds in alkylphenols by a chemomimetic biocatalytic system.

Du L, Dong S, Zhang X, Jiang C, Chen J, Yao L, Wang X, Wan X, Liu X, Wang X, Huang S, Cui Q, Feng Y, Liu SJ, Li S. Du L, et al. Among authors: wan x. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5129-E5137. doi: 10.1073/pnas.1702317114. Epub 2017 Jun 12. Proc Natl Acad Sci U S A. 2017. PMID: 28607077 Free PMC article.

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