Tu Z - Search Results

1

Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.

Chen Y, Zheng Y, Kang Y, Yang W, Niu Y, Guo X, Tu Z, Si C, Wang H, Xing R, Pu X, Yang SH, Li S, Ji W, Li XJ. Chen Y, et al. Among authors: tu z. Hum Mol Genet. 2015 Jul 1;24(13):3764-74. doi: 10.1093/hmg/ddv120. Epub 2015 Apr 9. Hum Mol Genet. 2015. PMID: 25859012 Free PMC article.

2

Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.

Yin P, Tu Z, Yin A, Zhao T, Yan S, Guo X, Chang R, Zhang L, Hong Y, Huang X, Zhou J, Wang Y, Li S, Li XJ. Yin P, et al. Among authors: tu z. Hum Mol Genet. 2015 Mar 1;24(5):1350-62. doi: 10.1093/hmg/ddu544. Epub 2014 Oct 24. Hum Mol Genet. 2015. PMID: 25343992 Free PMC article.

3

Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain.

Yang W, Wang G, Wang CE, Guo X, Yin P, Gao J, Tu Z, Wang Z, Wu J, Hu X, Li S, Li XJ. Yang W, et al. Among authors: tu z. J Neurosci. 2015 May 27;35(21):8345-58. doi: 10.1523/JNEUROSCI.0772-15.2015. J Neurosci. 2015. PMID: 26019347 Free PMC article.

4

CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases.

Tu Z, Yang W, Yan S, Guo X, Li XJ. Tu Z, et al. Mol Neurodegener. 2015 Aug 4;10:35. doi: 10.1186/s13024-015-0031-x. Mol Neurodegener. 2015. PMID: 26238861 Free PMC article. Review.

5

CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases.

Yang W, Tu Z, Sun Q, Li XJ. Yang W, et al. Among authors: tu z. Front Mol Neurosci. 2016 Apr 28;9:30. doi: 10.3389/fnmol.2016.00030. eCollection 2016. Front Mol Neurosci. 2016. PMID: 27199655 Free PMC article. Review.

6

Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos.

Tu Z, Yang W, Yan S, Yin A, Gao J, Liu X, Zheng Y, Zheng J, Li Z, Yang S, Li S, Guo X, Li XJ. Tu Z, et al. Sci Rep. 2017 Feb 3;7:42081. doi: 10.1038/srep42081. Sci Rep. 2017. PMID: 28155910 Free PMC article.

7

Use of CRISPR/Cas9 to model brain diseases.

Yan S, Tu Z, Li S, Li XJ. Yan S, et al. Among authors: tu z. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 2;81:488-492. doi: 10.1016/j.pnpbp.2017.04.003. Epub 2017 Apr 6. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 28392484 Free PMC article. Review.

8

Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate.

Zhao H, Tu Z, Xu H, Yan S, Yan H, Zheng Y, Yang W, Zheng J, Li Z, Tian R, Lu Y, Guo X, Jiang YH, Li XJ, Zhang YQ. Zhao H, et al. Among authors: tu z. Cell Res. 2017 Oct;27(10):1293-1297. doi: 10.1038/cr.2017.95. Epub 2017 Jul 25. Cell Res. 2017. PMID: 28741620 Free PMC article. No abstract available.

9

CRISPR: Established Editor of Human Embryos?

Li XJ, Tu Z, Yang W, Li S. Li XJ, et al. Among authors: tu z. Cell Stem Cell. 2017 Sep 7;21(3):295-296. doi: 10.1016/j.stem.2017.08.007. Cell Stem Cell. 2017. PMID: 28886363 Free PMC article.

10

A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease.

Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, Yang W, Zhao Y, Ouyang Z, Lai C, Yang H, Li L, Liu Q, Shi H, Xu G, Zhao H, Wei H, Pei Z, Li S, Lai L, Li XJ. Yan S, et al. Among authors: tu z. Cell. 2018 May 3;173(4):989-1002.e13. doi: 10.1016/j.cell.2018.03.005. Epub 2018 Mar 29. Cell. 2018. PMID: 29606351 Free PMC article.

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