Wang P - Search Results

1

Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter.

Jung K, Gupta N, Wang P, Lewis JT, Gopal K, Wu F, Ye X, Alshareef A, Abdulkarim BS, Douglas DN, Kneteman NM, Lai R. Jung K, et al. Among authors: wang p. Oncotarget. 2015 Apr 30;6(12):10366-73. doi: 10.18632/oncotarget.3590. Oncotarget. 2015. PMID: 25868977 Free PMC article.

2

Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells.

Wang P, Zhang J, Bellail A, Jiang W, Hugh J, Kneteman NM, Hao C. Wang P, et al. Cell Signal. 2007 Nov;19(11):2237-46. doi: 10.1016/j.cellsig.2007.06.001. Epub 2007 Jun 21. Cell Signal. 2007. PMID: 17693058

3

Proteome-wide identification of novel binding partners to the oncogenic fusion gene protein, NPM-ALK, using tandem affinity purification and mass spectrometry.

Wu F, Wang P, Young LC, Lai R, Li L. Wu F, et al. Among authors: wang p. Am J Pathol. 2009 Feb;174(2):361-70. doi: 10.2353/ajpath.2009.080521. Epub 2009 Jan 8. Am J Pathol. 2009. PMID: 19131589 Free PMC article.

4

Targeted quantitative mass spectrometric identification of differentially expressed proteins between Bax-expressing and deficient colorectal carcinoma cells.

Wang P, Lo A, Young JB, Song JH, Lai R, Kneteman NM, Hao C, Li L. Wang P, et al. J Proteome Res. 2009 Jul;8(7):3403-14. doi: 10.1021/pr9000477. J Proteome Res. 2009. PMID: 19425606

5

Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry.

Wang P, Wu F, Ma Y, Li L, Lai R, Young LC. Wang P, et al. J Biol Chem. 2010 Jan 1;285(1):95-103. doi: 10.1074/jbc.M109.059758. Epub 2009 Nov 2. J Biol Chem. 2010. PMID: 19887368 Free PMC article.

6

Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymphoma.

Wu F, Wang P, Zhang J, Young LC, Lai R, Li L. Wu F, et al. Among authors: wang p. Mol Cell Proteomics. 2010 Jul;9(7):1616-32. doi: 10.1074/mcp.M000153-MCP201. Epub 2010 Apr 14. Mol Cell Proteomics. 2010. PMID: 20393185 Free PMC article.

7

The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions.

Hegazy SA, Wang P, Anand M, Ingham RJ, Gelebart P, Lai R. Hegazy SA, et al. Among authors: wang p. J Biol Chem. 2010 Jun 25;285(26):19813-20. doi: 10.1074/jbc.M110.121988. Epub 2010 Apr 27. J Biol Chem. 2010. PMID: 20424160 Free PMC article.

8

Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential.

Wang P, Wu F, Zhang J, McMullen T, Young LC, Ingham RJ, Li L, Lai R. Wang P, et al. Carcinogenesis. 2011 Feb;32(2):146-53. doi: 10.1093/carcin/bgq229. Epub 2010 Nov 2. Carcinogenesis. 2011. PMID: 21045017

9

Fusion tyrosine kinase NPM-ALK Deregulates MSH2 and suppresses DNA mismatch repair function novel insights into a potent oncoprotein.

Young LC, Bone KM, Wang P, Wu F, Adam BA, Hegazy S, Gelebart P, Holovati J, Li L, Andrew SE, Lai R. Young LC, et al. Among authors: wang p. Am J Pathol. 2011 Jul;179(1):411-21. doi: 10.1016/j.ajpath.2011.03.045. Epub 2011 May 24. Am J Pathol. 2011. PMID: 21703420 Free PMC article.

10

Aberrant expression of the transcriptional factor Twist1 promotes invasiveness in ALK-positive anaplastic large cell lymphoma.

Zhang J, Wang P, Wu F, Li M, Sharon D, Ingham RJ, Hitt M, McMullen TP, Lai R. Zhang J, et al. Among authors: wang p. Cell Signal. 2012 Apr;24(4):852-8. doi: 10.1016/j.cellsig.2011.11.020. Epub 2011 Dec 8. Cell Signal. 2012. PMID: 22155737

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