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Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy.
Liechtenstein T, Perez-Janices N, Blanco-Luquin I, Goyvaerts C, Schwarze J, Dufait I, Lanna A, Ridder M, Guerrero-Setas D, Breckpot K, Escors D. Liechtenstein T, et al. Oncoimmunology. 2014 Jul 3;3(7):e945378. doi: 10.4161/21624011.2014.945378. eCollection 2014. Oncoimmunology. 2014. PMID: 25954597 Free PMC article.
Neurocognitive Function, Psychosocial Outcome, and Health-Related Quality of Life of the First-Generation Metastatic Melanoma Survivors Treated with Ipilimumab.
Rogiers A, Leys C, Lauwyck J, Schembri A, Awada G, Schwarze JK, De Cremer J, Theuns P, Maruff P, De Ridder M, Bernheim JL, Neyns B. Rogiers A, et al. Among authors: schwarze jk. J Immunol Res. 2020 Jul 21;2020:2192480. doi: 10.1155/2020/2192480. eCollection 2020. J Immunol Res. 2020. PMID: 32775464 Free PMC article. Clinical Trial.
Intratumoral Combinatorial Administration of CD1c (BDCA-1)+ Myeloid Dendritic Cells Plus Ipilimumab and Avelumab in Combination with Intravenous Low-Dose Nivolumab in Patients with Advanced Solid Tumors: A Phase IB Clinical Trial.
Schwarze JK, Awada G, Cras L, Tijtgat J, Forsyth R, Dufait I, Tuyaerts S, Van Riet I, Neyns B. Schwarze JK, et al. Vaccines (Basel). 2020 Nov 10;8(4):670. doi: 10.3390/vaccines8040670. Vaccines (Basel). 2020. PMID: 33182610 Free PMC article.
Intratumoral administration of CD1c (BDCA-1)+ and CD141 (BDCA-3)+ myeloid dendritic cells in combination with talimogene laherparepvec in immune checkpoint blockade refractory advanced melanoma patients: a phase I clinical trial.
Schwarze JK, Tijtgat J, Awada G, Cras L, Vasaturo A, Bagnall C, Forsyth R, Dufait I, Tuyaerts S, Van Riet I, Neyns B. Schwarze JK, et al. J Immunother Cancer. 2022 Sep;10(9):e005141. doi: 10.1136/jitc-2022-005141. J Immunother Cancer. 2022. PMID: 36113895 Free PMC article. Clinical Trial.
A randomized phase II clinical trial of stereotactic body radiation therapy (SBRT) and systemic pembrolizumab with or without intratumoral avelumab/ipilimumab plus CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells in solid tumors.
Vounckx M, Tijtgat J, Stevens L, Dirven I, Ilsen B, Vandenbroucke F, Raeymaeckers S, Vekens K, Forsyth R, Geeraerts X, Van Riet I, Schwarze JK, Tuyaerts S, Decoster L, De Ridder M, Dufait I, Neyns B. Vounckx M, et al. Among authors: schwarze jk. Cancer Immunol Immunother. 2024 Jul 2;73(9):167. doi: 10.1007/s00262-024-03751-0. Cancer Immunol Immunother. 2024. PMID: 38954010 Free PMC article. Clinical Trial.
38 results