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Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells.
Kanmogne GD, Singh S, Roy U, Liu X, McMillan J, Gorantla S, Balkundi S, Smith N, Alnouti Y, Gautam N, Zhou Y, Poluektova L, Kabanov A, Bronich T, Gendelman HE. Kanmogne GD, et al. Among authors: gautam n. Int J Nanomedicine. 2012;7:2373-88. doi: 10.2147/IJN.S29454. Epub 2012 May 8. Int J Nanomedicine. 2012. PMID: 22661891 Free PMC article.
Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.
Radhakrishnan P, Bryant VC, Blowers EC, Rajule RN, Gautam N, Anwar MM, Mohr AM, Grandgenett PM, Bunt SK, Arnst JL, Lele SM, Alnouti Y, Hollingsworth MA, Natarajan A. Radhakrishnan P, et al. Among authors: gautam n. Clin Cancer Res. 2013 Apr 15;19(8):2025-35. doi: 10.1158/1078-0432.CCR-12-2909. Epub 2013 Feb 26. Clin Cancer Res. 2013. PMID: 23444213 Free PMC article.
Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residence time and subsequent potency against primary murine breast tumors after IV administration.
Wakaskar RR, Bathena SP, Tallapaka SB, Ambardekar VV, Gautam N, Thakare R, Simet SM, Curran SM, Singh RK, Dong Y, Vetro JA. Wakaskar RR, et al. Among authors: gautam n. Pharm Res. 2015 Mar;32(3):1028-44. doi: 10.1007/s11095-014-1515-z. Epub 2014 Sep 16. Pharm Res. 2015. PMID: 25223962 Free PMC article.
519 results