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Page 1
Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators.
Chappie TA, Abdelmessih M, Ambroise CW, Boehm M, Cai M, Green M, Guilmette E, Steppan CM, Stevens LM, Wei L, Xi S, Hasson SA. Chappie TA, et al. Among authors: guilmette e. ACS Med Chem Lett. 2022 Jan 4;13(1):55-62. doi: 10.1021/acsmedchemlett.1c00396. eCollection 2022 Jan 13. ACS Med Chem Lett. 2022. PMID: 35059124 Free PMC article.
The Parkinson's disease-associated gene ITPKB protects against α-synuclein aggregation by regulating ER-to-mitochondria calcium release.
Apicco DJ, Shlevkov E, Nezich CL, Tran DT, Guilmette E, Nicholatos JW, Bantle CM, Chen Y, Glajch KE, Abraham NA, Dang LT, Kaynor GC, Tsai EA, Nguyen KH, Groot J, Liu Y, Weihofen A, Hurt JA, Runz H, Hirst WD. Apicco DJ, et al. Among authors: guilmette e. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2006476118. doi: 10.1073/pnas.2006476118. Proc Natl Acad Sci U S A. 2021. PMID: 33443159 Free PMC article.
Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice.
Hawley ZCE, Pardo ID, Cao S, Zavodszky MI, Casey F, Ferber K, Luo Y, Hana S, Chen SK, Doherty J, Costa R, Cullen P, Liu Y, Carlile TM, Chowdhury T, Doyle B, Clarner P, Mangaudis K, Guilmette E, Bourque S, Koske D, Nadella MVP, Trapa P, Hawes ML, Raitcheva D, Lo SC. Hawley ZCE, et al. Among authors: guilmette e. Mol Ther. 2025 Jan 8;33(1):215-234. doi: 10.1016/j.ymthe.2024.11.029. Epub 2024 Nov 19. Mol Ther. 2025. PMID: 39563026
17 results