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Redox-Mediated Suberoylanilide Hydroxamic Acid Sensitivity in Breast Cancer.
Chiaradonna F, Barozzi I, Miccolo C, Bucci G, Palorini R, Fornasari L, Botrugno OA, Pruneri G, Masullo M, Passafaro A, Galimberti VE, Fantin VR, Richon VM, Pece S, Viale G, Di Fiore PP, Draetta G, Pelicci PG, Minucci S, Chiocca S. Chiaradonna F, et al. Among authors: barozzi i. Antioxid Redox Signal. 2015 Jul 1;23(1):15-29. doi: 10.1089/ars.2014.6189. Epub 2015 May 27. Antioxid Redox Signal. 2015. PMID: 25897982 Free PMC article.
Pathology tissue-chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples.
Fanelli M, Amatori S, Barozzi I, Soncini M, Dal Zuffo R, Bucci G, Capra M, Quarto M, Dellino GI, Mercurio C, Alcalay M, Viale G, Pelicci PG, Minucci S. Fanelli M, et al. Among authors: barozzi i. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21535-40. doi: 10.1073/pnas.1007647107. Epub 2010 Nov 24. Proc Natl Acad Sci U S A. 2010. PMID: 21106756 Free PMC article.
A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance.
Santoro F, Botrugno OA, Dal Zuffo R, Pallavicini I, Matthews GM, Cluse L, Barozzi I, Senese S, Fornasari L, Moretti S, Altucci L, Pelicci PG, Chiocca S, Johnstone RW, Minucci S. Santoro F, et al. Among authors: barozzi i. Blood. 2013 Apr 25;121(17):3459-68. doi: 10.1182/blood-2012-10-461988. Epub 2013 Feb 25. Blood. 2013. PMID: 23440245 Free article.
Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion.
Nguyen VT, Barozzi I, Faronato M, Lombardo Y, Steel JH, Patel N, Darbre P, Castellano L, Győrffy B, Woodley L, Meira A, Patten DK, Vircillo V, Periyasamy M, Ali S, Frige G, Minucci S, Coombes RC, Magnani L. Nguyen VT, et al. Among authors: barozzi i. Nat Commun. 2015 Nov 27;6:10044. doi: 10.1038/ncomms10044. Nat Commun. 2015. PMID: 26610607 Free PMC article.
Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer.
Magnani L, Frige G, Gadaleta RM, Corleone G, Fabris S, Kempe MH, Verschure PJ, Barozzi I, Vircillo V, Hong SP, Perone Y, Saini M, Trumpp A, Viale G, Neri A, Ali S, Colleoni MA, Pruneri G, Minucci S. Magnani L, et al. Among authors: barozzi i. Nat Genet. 2017 Mar;49(3):444-450. doi: 10.1038/ng.3773. Epub 2017 Jan 23. Nat Genet. 2017. PMID: 28112739 Free PMC article.
Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer.
Patten DK, Corleone G, Győrffy B, Perone Y, Slaven N, Barozzi I, Erdős E, Saiakhova A, Goddard K, Vingiani A, Shousha S, Pongor LS, Hadjiminas DJ, Schiavon G, Barry P, Palmieri C, Coombes RC, Scacheri P, Pruneri G, Magnani L. Patten DK, et al. Among authors: barozzi i. Nat Med. 2018 Sep;24(9):1469-1480. doi: 10.1038/s41591-018-0091-x. Epub 2018 Jul 23. Nat Med. 2018. PMID: 30038216 Free PMC article.
Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy.
Hong SP, Chan TE, Lombardo Y, Corleone G, Rotmensz N, Bravaccini S, Rocca A, Pruneri G, McEwen KR, Coombes RC, Barozzi I, Magnani L. Hong SP, et al. Among authors: barozzi i. Nat Commun. 2019 Sep 2;10(1):3840. doi: 10.1038/s41467-019-11721-9. Nat Commun. 2019. PMID: 31477698 Free PMC article.
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation.
Ravasio R, Ceccacci E, Nicosia L, Hosseini A, Rossi PL, Barozzi I, Fornasari L, Zuffo RD, Valente S, Fioravanti R, Mercurio C, Varasi M, Mattevi A, Mai A, Pavesi G, Bonaldi T, Minucci S. Ravasio R, et al. Among authors: barozzi i. Sci Adv. 2020 Apr 8;6(15):eaax2746. doi: 10.1126/sciadv.aax2746. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32284990 Free PMC article.
76 results