NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action.
Jaquet V, Marcoux J, Forest E, Leidal KG, McCormick S, Westermaier Y, Perozzo R, Plastre O, Fioraso-Cartier L, Diebold B, Scapozza L, Nauseef WM, Fieschi F, Krause KH, Bedard K.
Jaquet V, et al. Among authors: krause kh.
Br J Pharmacol. 2011 Sep;164(2b):507-20. doi: 10.1111/j.1476-5381.2011.01439.x.
Br J Pharmacol. 2011.
PMID: 21501142
Free PMC article.