Beck-Sickinger AG - Search Results

1

Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight.

Kilian TM, Klöting N, Bergmann R, Els-Heindl S, Babilon S, Clément-Ziza M, Zhang Y, Beck-Sickinger AG, Chollet C. Kilian TM, et al. J Med Chem. 2015 May 28;58(10):4180-93. doi: 10.1021/jm501702q. Epub 2015 May 7. J Med Chem. 2015. PMID: 25905598

2

Novel peptide conjugates for tumor-specific chemotherapy.

Langer M, Kratz F, Rothen-Rutishauser B, Wunderli-Allenspach H, Beck-Sickinger AG. Langer M, et al. J Med Chem. 2001 Apr 26;44(9):1341-8. doi: 10.1021/jm001065f. J Med Chem. 2001. PMID: 11311056

3

Peptides as carrier for tumor diagnosis and treatment.

Langer M, Beck-Sickinger AG. Langer M, et al. Curr Med Chem Anticancer Agents. 2001 May;1(1):71-93. doi: 10.2174/1568011013354877. Curr Med Chem Anticancer Agents. 2001. PMID: 12678771 Review.

4

Facile and selective nanoscale labeling of peptides in solution by using photolabile protecting groups.

Koglin N, Lang M, Rennert R, Beck-Sickinger AG. Koglin N, et al. J Med Chem. 2003 Oct 9;46(21):4369-72. doi: 10.1021/jm0341251. J Med Chem. 2003. PMID: 14521401

5

In vitro gene delivery by a novel human calcitonin (hCT)-derived carrier peptide.

Krauss U, Müller M, Stahl M, Beck-Sickinger AG. Krauss U, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):51-4. doi: 10.1016/j.bmcl.2003.10.014. Bioorg Med Chem Lett. 2004. PMID: 14684296

6

Structure-activity studies of orexin a and orexin B at the human orexin 1 and orexin 2 receptors led to orexin 2 receptor selective and orexin 1 receptor preferring ligands.

Lang M, Söll RM, Dürrenberger F, Dautzenberg FM, Beck-Sickinger AG. Lang M, et al. J Med Chem. 2004 Feb 26;47(5):1153-60. doi: 10.1021/jm030982t. J Med Chem. 2004. PMID: 14971895

7

Biosynthesis of peptide hormones derived from precursor sequences.

von Eggelkraut-Gottanka R, Beck-Sickinger AG. von Eggelkraut-Gottanka R, et al. Curr Med Chem. 2004 Oct;11(20):2651-65. doi: 10.2174/0929867043364405. Curr Med Chem. 2004. PMID: 15544467 Review.

8

Identification of the key residue of calcitonin gene related peptide (CGRP) 27-37 to obtain antagonists with picomolar affinity at the CGRP receptor.

Lang M, De Pol S, Baldauf C, Hofmann HJ, Reiser O, Beck-Sickinger AG. Lang M, et al. J Med Chem. 2006 Jan 26;49(2):616-24. doi: 10.1021/jm050613s. J Med Chem. 2006. PMID: 16420047

9

Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands.

Merten N, Lindner D, Rabe N, Römpler H, Mörl K, Schöneberg T, Beck-Sickinger AG. Merten N, et al. J Biol Chem. 2007 Mar 9;282(10):7543-51. doi: 10.1074/jbc.M608902200. Epub 2007 Jan 4. J Biol Chem. 2007. PMID: 17204471 Free article.

10

Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.

Keller M, Pop N, Hutzler C, Beck-Sickinger AG, Bernhardt G, Buschauer A. Keller M, et al. J Med Chem. 2008 Dec 25;51(24):8168-72. doi: 10.1021/jm801018u. J Med Chem. 2008. PMID: 19053784

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